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myo-inositol oxygenase

Summary

Gene Symbol

MIOX

Aliases

kidney-specific protein 32

Organism

Homo sapiens (human)

External Links

NCBI Gene

55586

HGNC

14522

KEGG Gene ID

hsa:55586

PubChem

55586

Alliance of Genome Resources

HGNC:14522

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Iron
Metal-binding
Oxidoreductase
Phosphoprotein
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UGB7	Aldehyde reductase-like 6 Kidney-specific protein 32 Myo-inositol oxygenase Renal-specific oxidoreductase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
inositol catabolic process	IBA IDA ISS	18364358

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

small molecule catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

inositol catabolic process

organic substance catabolic process [inference]

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

inositol catabolic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

inositol metabolic process [inference]

inositol catabolic process

polyol catabolic process [inference]

inositol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

inositol catabolic process

small molecule catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

inositol catabolic process

organic substance metabolic process [inference]

organic substance catabolic process [inference]

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

inositol catabolic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

polyol metabolic process [inference]

inositol metabolic process [inference]

inositol catabolic process

polyol catabolic process [inference]

inositol catabolic process

alcohol catabolic process [inference]

polyol catabolic process [inference]

inositol catabolic process

organic hydroxy compound catabolic process [inference]

alcohol catabolic process [inference]

polyol catabolic process [inference]

inositol catabolic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytosol
cytoplasm	ISS
inclusion body	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

intracellular anatomical structure [inference]

inclusion body

Displaying **all 4** entries
GO Term	Evidence Code	PMID
ferric iron binding	IDA	18364358
inositol oxygenase activity	IBA IDA ISS	18364358
oxidoreductase activity, acting on NAD(P)H	IEA
aldo-keto reductase (NADP) activity	ISS

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

inositol oxygenase activity

oxidoreductase activity, acting on CH-OH group of donors [inference]

oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor [inference]

aldo-keto reductase (NADP) activity

oxidoreductase activity, acting on NAD(P)H

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen [inference]

inositol oxygenase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

iron ion binding [inference]

ferric iron binding

sulfur compound binding [inference]

ferric iron binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Inositol oxygenase

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 5** entries
Gene Ontology
inositol catabolic process
inositol oxygenase activity
iron ion binding
metal ion binding
oxidoreductase activity

Displaying 1 entry
InterPro
Inositol oxygenase

KEGG BRITE Database

Orthology

K00469

Name

inositol oxygenase [EC:1.13.99.1]

References

11716759

Rhea

O₂ + myo-inositol

H₂O + H⁺ + D-glucuronate

Enzyme

1.13.99.1

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP003601
Gene Name: myo-inositol oxygenase

Ortholog

Displaying entries **31 - 40** of 69 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Octodon degus	101576030			OCTDE21261
Jaculus jaculus	101602751			JACJA01611
Mustela putorius furo	101685596			MUSPF03600
Ictidomys tridecemlineatus	101977950			ICTTR13283
Chinchilla lanigera	102030176			CHILA04693
Capra hircus	102188934			CAPHI25944
Myotis lucifugus	102428143			MYOLU17037
Astyanax mexicanus	103025371			ASTMX02602
Erinaceus europaeus	103110193			ERIEU03034
Callorhinchus milii	103190008			CALMI42781

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024