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procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3

Summary

Gene Symbol

plod3

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

556077

KEGG Gene ID

dre:556077

PubChem

556077

Alliance of Genome Resources

ZFIN:ZDB-GENE-021031-4

Annotation

Keyword

Dioxygenase
Endoplasmic reticulum
Glycoprotein
Iron
Membrane
Metal-binding
Proteomics identification
Reference proteome
Signal
Vitamin C

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A3KNH4
A0A8M2B9A3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
neural crest cell migration	IMP	23349938
lens development in camera-type eye	IMP	37947618
motor neuron axon guidance	IMP	10393124 12482713 16731508
collagen fibril organization	IBA

GO Hierarchy

biological process

cellular process [inference]

cell motility [inference]

cell migration [inference]

ameboidal-type cell migration [inference]

mesenchymal cell migration [inference]

neural crest cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance [inference]

motor neuron axon guidance

extracellular structure organization [inference]

extracellular matrix organization [inference]

collagen fibril organization

external encapsulating structure organization [inference]

extracellular matrix organization [inference]

collagen fibril organization

supramolecular fiber organization [inference]

collagen fibril organization

developmental process [inference]

anatomical structure development [inference]

lens development in camera-type eye

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GO Term	Evidence Code	PMID
extracellular space	IBA
endoplasmic reticulum	IBA
endoplasmic reticulum	IEA
endoplasmic reticulum membrane	IEA
rough endoplasmic reticulum	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

rough endoplasmic reticulum

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

rough endoplasmic reticulum

Golgi apparatus

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
iron ion binding	IEA
procollagen-lysine 5-dioxygenase activity	IBA
procollagen-lysine 5-dioxygenase activity	IEA
oxidoreductase activity	IEA
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

2-oxoglutarate-dependent dioxygenase activity [inference]

peptidyl-lysine 5-dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

dioxygenase activity

2-oxoglutarate-dependent dioxygenase activity [inference]

peptidyl-lysine 5-dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

glucosyltransferase activity [inference]

procollagen glucosyltransferase activity

catalytic activity, acting on a protein [inference]

procollagen glucosyltransferase activity

peptidyl-lysine 5-dioxygenase activity [inference]

procollagen-lysine 5-dioxygenase activity

binding [inference]

carbohydrate binding [inference]

monosaccharide binding [inference]

L-ascorbic acid binding

small molecule binding [inference]

vitamin binding [inference]

L-ascorbic acid binding

organic acid binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

monosaccharide binding [inference]

L-ascorbic acid binding

heterocyclic compound binding [inference]

L-ascorbic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

iron ion binding

organic cyclic compound binding [inference]

L-ascorbic acid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Procollagen-lysine,2-oxoglutarate 5-dioxygenase

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 7** entries
Gene Ontology
L-ascorbic acid binding
dioxygenase activity
iron ion binding
metal ion binding
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
oxidoreductase activity
procollagen-proline 4-dioxygenase activity

Displaying **all 4** entries
InterPro
Oxoglutarate/iron-dependent dioxygenase
Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain
Prolyl 4-hydroxylase, alpha subunit
Prolyl 4-hydroxylase

KEGG BRITE Database

Orthology

K13646

Name

lysyl hydroxylase/galactosyltransferase/glucosyltransferase [EC:1.14.11.4 2.4.1.50 2.4.1.66]

References

Rhea

RHEA:16569

O₂ + 2-oxoglutarate

CO₂ + succinate

Enzyme

1.14.11.4

PMID

Ortholog

Displaying entries **1 - 10** of 66 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	5351	FB:FBgn0036147
Drosophila melanogaster	5352	FB:FBgn0036147
Homo sapiens	8985	Xenbase:XB-GENE-5916631	HUMAN90460
Drosophila melanogaster	18822	FB:FBgn0036147
Drosophila melanogaster	26432	FB:FBgn0036147
Mus musculus	26433	Xenbase:XB-GENE-5916631	MOUSE47276
Xenopus tropicalis	39265	Xenbase:XB-GENE-5916631
Rattus norvegicus	288583	Xenbase:XB-GENE-5916631	RATNO05275
Xenopus tropicalis	380138	Xenbase:XB-GENE-5916631
Pan troglodytes	463618		PANTR41006

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements