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Repository for lectin-assisted multimodality data

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Tools

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Search Tools

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Guidelines

MIRAGE

catechol-O-methyltransferase a

Summary

Gene Symbol

comta

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

561372

PubChem

561372

Alliance of Genome Resources

ZFIN:ZDB-GENE-050913-117

Annotation

Keyword

Alternative splicing
Catecholamine metabolism
Glycoprotein
Magnesium
Metal-binding
Methyltransferase
Neurotransmitter degradation
Reference proteome
S-adenosyl-L-methionine
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
F4ZGF2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
catecholamine metabolic process	IEA
methylation	IEA
developmental process	IBA
dopamine metabolic process	IBA
catecholamine catabolic process	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

methylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic substance metabolic process [inference]

organic cyclic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organonitrogen compound metabolic process [inference]

amine metabolic process [inference]

biogenic amine metabolic process [inference]

catecholamine metabolic process

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organonitrogen compound catabolic process [inference]

amine catabolic process [inference]

cellular biogenic amine catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

organic hydroxy compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

phenol-containing compound metabolic process [inference]

catechol-containing compound metabolic process [inference]

catecholamine metabolic process

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenol-containing compound catabolic process [inference]

catechol-containing compound catabolic process [inference]

catecholamine catabolic process

developmental process

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular region	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
magnesium ion binding	IEA
methyltransferase activity	IEA
O-methyltransferase activity	IEA
catechol O-methyltransferase activity	IDA	21371608
catechol O-methyltransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity

O-methyltransferase activity

catechol O-methyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

catechol O-methyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

magnesium ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

o-methyltransferase

Functional Category

G: Carbohydrate transport and metabolism
I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis

Displaying **all 6** entries
Gene Ontology
O-methyltransferase activity
catecholamine catabolic process
catecholamine metabolic process
dopamine metabolic process
methylation
transferase activity

Displaying **all 2** entries
InterPro
Class I-like SAM-dependent O-methyltransferase
S-adenosyl-L-methionine-dependent methyltransferase superfamily

Ortholog

Displaying entries **31 - 40** of 59 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Myotis lucifugus	102428822		MYOLU12064
Astyanax mexicanus	103025058		ASTMX04013
Erinaceus europaeus	103123291		ERIEU02845
Callorhinchus milii	103183994		CALMI28692
Chlorocebus sabaeus	103222988		CHLSB07121
Carlito syrichta	103262083		CARSF05188
Ursus maritimus	103669258		URSMA27549
Nannospalax galili	103742059		NANGA20735
Serinus canaria	103818085		SERCA12886
Rhinopithecus roxellana	104681986		RHIRO39893

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025