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adhesion G protein-coupled receptor G6

Summary

Gene Symbol

adgrg6

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

561970

PubChem

561970

Alliance of Genome Resources

ZFIN:ZDB-GENE-041014-357

Annotation

Keyword

Cell membrane
Disulfide bond
G-protein coupled receptor
Glycoprotein
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
C6KFA3	G-protein coupled receptor 126

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	PMID
ossification	IMP	23666238
mitochondrion organization	IMP	24082093
signal transduction	IEA
cell surface receptor signaling pathway	IDA	25118328
cell surface receptor signaling pathway	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

cyclic-nucleotide-mediated signaling [inference]

cAMP-mediated signaling

ensheathment of neurons [inference]

axon ensheathment [inference]

peripheral nervous system axon ensheathment [inference]

myelination in peripheral nervous system

myelination

myelination in peripheral nervous system

myelination of lateral line nerve axons [inference]

myelination of posterior lateral line nerve axons

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation [inference]

Schwann cell differentiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

mitochondrion organization

cellular component assembly [inference]

cellular component assembly involved in morphogenesis [inference]

myelin assembly [inference]

peripheral nervous system myelin formation

multicellular organismal process [inference]

ossification

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

cellular component assembly involved in morphogenesis [inference]

myelin assembly [inference]

peripheral nervous system myelin formation

tube formation [inference]

tube closure [inference]

semicircular canal fusion

trabecula formation [inference]

heart trabecula formation

anatomical structure development [inference]

animal organ development [inference]

sensory organ development [inference]

ear development

heart development

cellular developmental process [inference]

cell differentiation [inference]

glial cell differentiation [inference]

Schwann cell differentiation

biological regulation [inference]

regulation of biological process [inference]

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of angiogenesis [inference]

regulation of sprouting angiogenesis

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

regulation of sprouting angiogenesis

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway

intracellular signal transduction [inference]

second-messenger-mediated signaling [inference]

cyclic-nucleotide-mediated signaling [inference]

cAMP-mediated signaling

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of vasculature development [inference]

regulation of angiogenesis [inference]

regulation of sprouting angiogenesis

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
plasma membrane	IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
transmembrane signaling receptor activity	IEA
G protein-coupled receptor activity	IDA	25118328
G protein-coupled receptor activity	IMP	19745155
G protein-coupled receptor activity	IBA
G protein-coupled receptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

laminin binding

protein-containing complex binding [inference]

collagen binding

extracellular matrix binding

laminin binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity

G protein-coupled receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

G-protein coupled receptor

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
cell surface receptor signaling pathway

Displaying **all 3** entries
InterPro
GPCR, family 2, secretin-like
GPCR, family 2-like, 7TM
GPS motif

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	14766	FB:FBgn0039821
Homo sapiens	57211	HGNC:13841	HUMAN86815
Drosophila melanogaster	84873	FB:FBgn0039821
Mus musculus	215798	HGNC:13841	MOUSE02004
Drosophila melanogaster	239853	FB:FBgn0039821
Rattus norvegicus	308376		RATNO17652
Drosophila melanogaster	382045	FB:FBgn0039821
Pan troglodytes	463034		PANTR39209
Canis lupus familiaris	484013		CANLF00167
Bos taurus	534326		BOVIN35903