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ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2)
Summary
- Gene Symbol
-
- adamts5
- Organism
- Danio rerio (zebrafish)
Annotation
- Keyword
-
- Calcium
- Cleavage on pair of basic residues
- Disulfide bond
- Glycoprotein
- Metal-binding
- Metalloprotease
- Reference proteome
- Secreted
- Signal
- Zinc
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| G3G3J8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis |
|
|
| heart development | ||
| extracellular matrix organization |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region |
|
|
| collagen-containing extracellular matrix |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| metalloendopeptidase activity |
|
|
| zinc ion binding |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- A disintegrin and metalloproteinase with thrombospondin motifs
- Functional Category
-
- K: Transcription
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| extracellular matrix organization |
| metal ion binding |
| metalloendopeptidase activity |
| metallopeptidase activity |
| proteolysis |
| zinc ion binding |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 101610021 | JACJA05248 | ||
| 101680971 | MUSPF11361 | ||
| 102021943 | CHILA01827 | ||
| 102145254 | MACFA28628 | ||
| 102172097 | CAPHI11622 | ||
| 102234961 | XIPMA23064 | ||
| 102294136 | HAPBU06604 | ||
| 102436476 | MYOLU09676 | ||
| 102444235 | PELSI17027 | ||
| 102694374 | LEPOC04641 |
