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aldehyde dehydrogenase 9, subfamily A1

Summary

Gene Symbol

Aldh9a1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56752

PubChem

56752

Alliance of Genome Resources

MGI:1861622

Annotation

Keyword

Acetylation
Alternative initiation
Cytoplasm
Direct protein sequencing
NAD
Oxidoreductase
Reference proteome
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q3V1N7	Aldehyde dehydrogenase family 9 member A1 Formaldehyde dehydrogenase Gamma-aminobutyraldehyde dehydrogenase
Q3TMT4	Aldehyde dehydrogenase family 9 member A1 Formaldehyde dehydrogenase Gamma-aminobutyraldehyde dehydrogenase
Q9JLJ2	Aldehyde dehydrogenase family 9 member A1 Formaldehyde dehydrogenase Gamma-aminobutyraldehyde dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
cellular aldehyde metabolic process	ISS
cellular aldehyde metabolic process	ISO
carnitine metabolic process	IDA	10702312
carnitine biosynthetic process	IDA	10702312
carnitine biosynthetic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular metabolic process [inference]

cellular aldehyde metabolic process

cellular modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular nitrogen compound metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organic substance metabolic process [inference]

cellular aldehyde metabolic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process

cellular modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular nitrogen compound metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cytoplasm	ISO
mitochondrion	HDA	18614015
cytosol	ISO	10702312
cytosol	IDA	10702312

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
aldehyde dehydrogenase (NAD+) activity	ISS
aldehyde dehydrogenase (NAD+) activity	ISO
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IDA	10702312
formaldehyde dehydrogenase activity	ISS
formaldehyde dehydrogenase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

aldehyde dehydrogenase [NAD(P)+] activity [inference]

aldehyde dehydrogenase (NAD+) activity

4-trimethylammoniobutyraldehyde dehydrogenase activity

binding [inference]

protein binding [inference]

identical protein binding

small molecule binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

amine binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Aldehyde

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
oxidoreductase activity

Displaying **all 6** entries
InterPro
Aldehyde dehydrogenase domain
Aldehyde dehydrogenase, C-terminal
Aldehyde dehydrogenase, N-terminal
Aldehyde dehydrogenase, cysteine active site
Aldehyde dehydrogenase, glutamic acid active site
Aldehyde/histidinol dehydrogenase

Ortholog

Displaying entries **1 - 10** of 69 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	223	Xenbase:XB-GENE-951247	HUMAN53396
Xenopus tropicalis	56752	Xenbase:XB-GENE-951247
Rattus norvegicus	64040		RATNO07372
Pan troglodytes	457478		PANTR22903
Canis lupus familiaris	478991		CANLF14376
Bos taurus	537539		BOVIN25464
Macaca mulatta	695383		MACMU22052
Danio rerio	100005587		DANRE43150
Danio rerio	100006238		DANRE43101
Equus caballus	100058551		HORSE35621