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aldehyde dehydrogenase 9, subfamily A1

Summary

Gene Symbol

Aldh9a1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

56752

PubChem

56752

Alliance of Genome Resources

MGI:1861622

Annotation

Keyword

Acetylation
Alternative initiation
Cytoplasm
Direct protein sequencing
NAD
Oxidoreductase
Reference proteome
Signal

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q3V1N7	Aldehyde dehydrogenase family 9 member A1 Formaldehyde dehydrogenase Gamma-aminobutyraldehyde dehydrogenase
Q3TMT4	Aldehyde dehydrogenase family 9 member A1 Formaldehyde dehydrogenase Gamma-aminobutyraldehyde dehydrogenase
Q9JLJ2	Aldehyde dehydrogenase family 9 member A1 Formaldehyde dehydrogenase Gamma-aminobutyraldehyde dehydrogenase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cellular aldehyde metabolic process	ISO ISS
carnitine biosynthetic process	IDA IEA	10702312
carnitine metabolic process	IDA	10702312
protein homotetramerization	ISO ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular metabolic process [inference]

cellular aldehyde metabolic process

cellular modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular nitrogen compound metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organic substance metabolic process [inference]

cellular aldehyde metabolic process

organonitrogen compound metabolic process [inference]

cellular modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aldehyde metabolic process

cellular modified amino acid metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular modified amino acid biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular nitrogen compound metabolic process [inference]

amino-acid betaine metabolic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

carnitine metabolic process

carnitine biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amino-acid betaine biosynthetic process [inference]

carnitine biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization [inference]

protein homotetramerization

protein tetramerization [inference]

protein homotetramerization

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mitochondrion	HDA	18614015
cytosol	IDA ISO	10702312
cytoplasm	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
identical protein binding	ISO
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity
small molecule binding	ISO
formaldehyde dehydrogenase activity	ISO ISS
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	IDA	10702312

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors [inference]

oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

aldehyde dehydrogenase [NAD(P)+] activity [inference]

aldehyde dehydrogenase (NAD+) activity

binding [inference]

protein binding [inference]

identical protein binding

small molecule binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

amine binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

NAD binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

4-trimethylaminobutyraldehyde dehydrogenase

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
I: Lipid transport and metabolism
K: Transcription

Displaying **all 5** entries
Gene Ontology
4-trimethylammoniobutyraldehyde dehydrogenase activity
aminobutyraldehyde dehydrogenase activity
betaine-aldehyde dehydrogenase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
oxidoreductase activity

Displaying **all 6** entries
InterPro
Aldehyde dehydrogenase domain
Aldehyde dehydrogenase, C-terminal
Aldehyde dehydrogenase, N-terminal
Aldehyde dehydrogenase, cysteine active site
Aldehyde dehydrogenase, glutamic acid active site
Aldehyde/histidinol dehydrogenase

Ortholog

Displaying entries **1 - 10** of **109** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	223		HGNC:412	HUMAN53396
Rattus norvegicus	64040	10116_1:0040fc	RGD:68409	RATNO07372
Caenorhabditis elegans	176056		WB:WBGene00000118
Caenorhabditis elegans	185679		WB:WBGene00000117
Danio rerio	399481		ZFIN:ZDB-GENE-040120-5
Xenopus tropicalis	448752		Xenbase:XB-GENE-951247
Pan troglodytes	457478			PANTR22903
Canis lupus familiaris	478991			CANLF14376
Bos taurus	537539			BOVIN25464
Macaca mulatta	695383			MACMU22052