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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
Summary
- Gene Symbol
-
- C1GALT1
- Aliases
-
- C1GALT
- T-synthase
- core 1 beta3-Gal-T
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Alternative splicing
- Angiogenesis
- Developmental protein
- Differentiation
- Disulfide bond
- Glycosyltransferase
- Manganese
- Metal-binding
- Nucleotide-binding
- Phosphoprotein
- Reference proteome
- Signal-anchor
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| A0A024RA32 |
|
| Q9NS00 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| O-glycan processing, core 1 | ||
| protein O-linked glycosylation | ||
| angiogenesis | ||
| kidney development | ||
| intestinal epithelial cell development |
| GO Term | Evidence Code | PMID |
|---|---|---|
| membrane | ||
| Golgi membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity | ||
| metal ion binding | ||
| protein binding | ||
| nucleotide binding |
GO Hierarchy
Human Protein Atlas
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
GlycoGene Database (GGDB)
- GGDB ID
- gg075
- Gene Symbol
-
- C1GALT1
- Reactions
G57321FI
G00031MO
| Donor | Acceptor | Product | Reference |
|---|---|---|---|
| UDP-Gal |
G00035MO
|
- Orthologous Gene
| Species | Protein | mRNA |
|---|---|---|
| Rattus norvegicus | NP_075239 | NM_022950 |
| Drosophila melanogaster | NP_723428 | NM_164840 |
| Caenorhabditis elegans | NP_499293 | NM_066892 |
| Mus musculus | NP_443719 | NM_052993 |
KEGG BRITE Database
Rhea
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:114 | heart disease | |
| DOID:11934 | head and neck cancer | |
| DOID:1287 | cardiovascular system disease | |
| DOID:1425 | pyoureter | |
| DOID:1520 | colon carcinoma | |
| DOID:1588 | thrombocytopenia | |
| DOID:1612 | breast cancer | |
| DOID:162 | cancer | |
| DOID:219 | colon cancer | |
| DOID:235 | colonic benign neoplasm |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 176455 | WB:WBGene00008019 | ||
| 32896 | FB:FBgn0030984 | ||
| 33482 | FB:FBgn0031469 | ||
| 33485 | FB:FBgn0031472 | ||
| 34215 | FB:FBgn0032078 | ||
| 35792 | FB:FBgn0033271 | ||
| 103185987 | CALMI33593 | ||
| 102345499 | LATCH11102 | ||
| 102690951 | LEPOC02736 | ||
| 337131 | ZFIN:ZDB-GENE-030131-9075 |
