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twisted gastrulation BMP signaling modulator 1

Summary

Gene Symbol

TWSG1

Organism

Homo sapiens (human)

External Links

NCBI Gene

57045

PubChem

57045

Alliance of Genome Resources

HGNC:12429

Annotation

Keyword

Alternative splicing
Developmental protein
Glycoprotein
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9GZX9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 17 in total

1

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GO Term	Evidence Code	PMID
ossification	IEA
mesoderm formation	IEA
negative regulation of cytokine production	IDA	17164348
chondrocyte differentiation	IEA
salivary gland morphogenesis	IEA

GO Hierarchy

biological process

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

cellular developmental process [inference]

cell differentiation [inference]

chondrocyte differentiation

cell development [inference]

hemopoiesis

multicellular organismal process [inference]

ossification

developmental process [inference]

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

gland morphogenesis [inference]

salivary gland morphogenesis

anatomical structure formation involved in morphogenesis [inference]

formation of primary germ layer [inference]

mesoderm formation

anatomical structure development [inference]

forebrain development

cell development [inference]

hemopoiesis

animal organ development [inference]

sensory organ development [inference]

eye development [inference]

camera-type eye development

cellular developmental process [inference]

cell differentiation [inference]

chondrocyte differentiation

cell development [inference]

hemopoiesis

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell activation [inference]

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

regulation of BMP signaling pathway

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of cellular response to transforming growth factor beta stimulus [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of metabolic process [inference]

negative regulation of biosynthetic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

regulation of BMP signaling pathway

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of cellular response to transforming growth factor beta stimulus [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of cellular response to growth factor stimulus [inference]

regulation of BMP signaling pathway

negative regulation of cellular response to growth factor stimulus [inference]

negative regulation of BMP signaling pathway

regulation of cellular response to transforming growth factor beta stimulus [inference]

regulation of transforming growth factor beta receptor signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

positive regulation of cellular response to transforming growth factor beta stimulus [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

regulation of developmental process [inference]

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

negative regulation of osteoblast differentiation

negative regulation of developmental process [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

enzyme-linked receptor protein signaling pathway [inference]

transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

transforming growth factor beta receptor superfamily signaling pathway [inference]

BMP signaling pathway

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

regulation of transforming growth factor beta receptor signaling pathway [inference]

positive regulation of transforming growth factor beta receptor signaling pathway

regulation of BMP signaling pathway

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of intracellular signal transduction [inference]

regulation of SMAD protein signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

regulation of cell adhesion [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of cell-cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of leukocyte cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of cellular metabolic process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of leukocyte proliferation [inference]

regulation of mononuclear cell proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of cell differentiation [inference]

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

negative regulation of osteoblast differentiation

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of SMAD protein signal transduction

negative regulation of cellular process [inference]

negative regulation of cell adhesion [inference]

negative regulation of cell-cell adhesion [inference]

negative regulation of leukocyte cell-cell adhesion [inference]

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of cell population proliferation [inference]

negative regulation of leukocyte proliferation [inference]

negative regulation of mononuclear cell proliferation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway [inference]

negative regulation of BMP signaling pathway

negative regulation of cellular metabolic process [inference]

negative regulation of cellular biosynthetic process [inference]

negative regulation of macromolecule biosynthetic process [inference]

negative regulation of gene expression [inference]

negative regulation of cytokine production

negative regulation of cell differentiation [inference]

negative regulation of osteoblast differentiation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell activation [inference]

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of multicellular organismal process [inference]

regulation of cytokine production [inference]

negative regulation of cytokine production

regulation of cell activation [inference]

regulation of leukocyte activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of lymphocyte activation [inference]

regulation of lymphocyte proliferation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of T cell activation [inference]

regulation of T cell proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of alpha-beta T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell activation [inference]

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

regulation of CD4-positive, alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of multicellular organismal process [inference]

negative regulation of cytokine production

negative regulation of cell activation [inference]

negative regulation of leukocyte activation [inference]

negative regulation of lymphocyte activation [inference]

negative regulation of lymphocyte proliferation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of T cell activation [inference]

negative regulation of T cell proliferation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of alpha-beta T cell activation [inference]

negative regulation of alpha-beta T cell proliferation [inference]

negative regulation of CD4-positive, alpha-beta T cell proliferation

negative regulation of CD4-positive, alpha-beta T cell activation

negative regulation of CD4-positive, alpha-beta T cell proliferation

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	25416956 32296183 32814053
heparin binding	IEA
transforming growth factor beta binding	IDA	17164348

GO Hierarchy

molecular function

binding [inference]

protein binding

growth factor binding [inference]

transforming growth factor beta binding

cytokine binding [inference]

transforming growth factor beta binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Twisted gastrulation

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
InterPro
Twisted gastrulation (Tsg) protein

Ortholog

Displaying entries **1 - 10** of 92 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	32160	Xenbase:XB-GENE-487717
Xenopus tropicalis	57045	Xenbase:XB-GENE-487717
Mus musculus	65960	Xenbase:XB-GENE-487717	MOUSE20570
Danio rerio	84037		DANRE29747
Xenopus tropicalis	259304	Xenbase:XB-GENE-487717
Rattus norvegicus	363294		RATNO43220
Xenopus tropicalis	379560	Xenbase:XB-GENE-483445
Xenopus tropicalis	399387	Xenbase:XB-GENE-483445
Pan troglodytes	455294		PANTR15875
Bos taurus	537290		BOVIN19637

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements