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Guidelines

MIRAGE

protein tyrosine phosphatase non-receptor type 7

Summary

Gene Symbol

PTPN7

Organism

Homo sapiens (human)

External Links

NCBI Gene

5778

PubChem

5778

Alliance of Genome Resources

HGNC:9659

Annotation

Keyword

3D-structure
Alternative splicing
Cytoskeleton
Oxidation
Phosphoprotein
Protein phosphatase
Receptor
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P35236	Hematopoietic protein-tyrosine phosphatase Protein-tyrosine phosphatase LC-PTP
B4DZD9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
MAPK cascade	TAS
chromatin remodeling	IEA
protein dephosphorylation	TAS	1530918
signal transduction	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular process [inference]

signal transduction

intracellular signal transduction [inference]

MAPK cascade

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

intracellular signal transduction [inference]

MAPK cascade

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
nucleoplasm	TAS
cytoplasm	IDA	10940933 14613483
cytosol	TAS
cytosol	IDA	10940933
cytoplasmic side of plasma membrane	IDA	10940933

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

spindle [inference]

mitotic spindle

cytoskeleton [inference]

microtubule cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

spindle [inference]

mitotic spindle

cytoskeleton [inference]

microtubule cytoskeleton

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein tyrosine phosphatase activity	IBA
non-membrane spanning protein tyrosine phosphatase activity	TAS
protein binding	IPI	10415025 12583813 12592337 25241761 25416956 32296183
protein tyrosine phosphatase activity, metal-dependent	IEA
histone H2AXY142 phosphatase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

histone modifying activity [inference]

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying entries **51 - 60** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Lepisosteus oculatus	102697085		LEPOC11712
Erinaceus europaeus	103112630		ERIEU03414
Ursus maritimus	103657718		URSMA23184
Serinus canaria	103822355		SERCA19151
Rhinopithecus roxellana	104674513		RHIRO16803
Macaca nemestrina	105484733		MACNE02895
Mandrillus leucophaeus	105547104		MANLE04314
Cercocebus atys	105575474		CERAT25410
Propithecus coquereli	105819621		PROCO27179
Dipodomys ordii	105986370		DIPOR10263

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GlyCosmos Portal v4.1.1

Last updated: February 17, 2025