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MIRAGE
protein tyrosine phosphatase receptor type B
Summary
- Gene Symbol
-
- PTPRB
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Angiogenesis
- Glycoprotein
- Phosphoprotein
- Protein phosphatase
- Proteomics identification
- Reference proteome
- Repeat
- Signal
- Transmembrane
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| angiogenesis | ||
| osteoblast differentiation | ||
| chromatin remodeling | ||
| protein dephosphorylation | ||
| phosphate-containing compound metabolic process |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| specific granule membrane | ||
| receptor complex | ||
| receptor complex |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| non-membrane spanning protein tyrosine phosphatase activity | ||
| transmembrane receptor protein tyrosine phosphatase activity | ||
| protein binding | ||
| protein tyrosine phosphatase activity, metal-dependent | ||
| cadherin binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Receptor-type tyrosine-protein phosphatase beta
- Functional Category
-
- G: Carbohydrate transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| angiogenesis |
| cadherin binding |
| InterPro |
|---|
| Fibronectin type III superfamily |
| Fibronectin type III |
| Immunoglobulin-like fold |
| PTPRJ, transmembrane domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0001816 | angiosarcoma | |
| DOID:0060108 | brain glioma | |
| DOID:0080199 | colorectal carcinoma | |
| DOID:1115 | sarcoma | |
| DOID:3068 | glioblastoma | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:4511 | breast angiosarcoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 5787 | Xenbase:XB-GENE-991728 | ||
| 19263 | Xenbase:XB-GENE-991728 | MOUSE01567 | |
| 32115 | Xenbase:XB-GENE-991728 | ||
| 174437 | Xenbase:XB-GENE-991728 | ||
| 314843 | RATNO37730 | ||
| 452074 | PANTR06404 | ||
| 481162 | CANLF01422 | ||
| 505696 | BOVIN29412 | ||
| 545902 | WB:WBGene00009717 | ||
| 718564 | MACMU04577 |
