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exostosin-like glycosyltransferase 2

Summary

Gene Symbol

Extl2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

58193

KEGG Gene ID

mmu:58193

PubChem

58193

Alliance of Genome Resources

MGI:1889574

Annotation

Keyword

3D-structure
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Glycosyltransferase
Manganese
Metal-binding
Proteomics identification
Reference proteome
Signal
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q9ES89	Alpha-1,4-N-acetylhexosaminyltransferase EXTL2 Alpha-GalNAcT EXTL2 EXT-related protein 2 Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase
Q8C089
Q3TSR0

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
N-acetylglucosamine metabolic process	ISO
N-acetylglucosamine metabolic process	IMP	12562774
UDP-N-acetylgalactosamine metabolic process	ISO
UDP-N-acetylgalactosamine metabolic process	IMP	12562774

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

phosphorus metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

organic substance metabolic process [inference]

carbohydrate derivative metabolic process [inference]

amino sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

glucosamine-containing compound metabolic process [inference]

N-acetylglucosamine metabolic process

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

phosphorus metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleotide-sugar metabolic process [inference]

UDP-N-acetylgalactosamine metabolic process

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nucleoplasm	ISO
nucleoplasm	IEA
endoplasmic reticulum	ISO
endoplasmic reticulum membrane	IEA
cytosol	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	ISO
glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity	IEA
glycosaminoglycan binding	IMP	12562774
glycosyltransferase activity
manganese ion binding	IMP	12562774

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity

acetylgalactosaminyltransferase activity [inference]

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity [inference]

glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity

acetylgalactosaminyltransferase activity [inference]

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

manganese ion binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Exostosin-like

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
transferase activity

Displaying **all 2** entries
InterPro
Glycosyl transferase 64 domain
Nucleotide-diphospho-sugar transferases

Rhea

RHEA:16221

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.223

PMID

Ortholog

Displaying entries **21 - 30** of 81 in total

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Species	Gene ID	Orthologous MAtrix
Oreochromis niloticus	100711437	ORENI26706
Cavia porcellus	100732343	CAVPO01587
Cricetulus griseus	100761218	CRIGR23499
Sarcophilus harrisii	100914736	SARHA01702
Otolemur garnettii	100959711	OTOGA16667
Pan paniscus	100977184	PANPA01921
Papio anubis	101013377	PAPAN21234
Saimiri boliviensis boliviensis	101043244	SAIBB21873
Takifugu rubripes	101066160	TAKRU31565
Felis catus	101089128	FELCA18861

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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OrthoDB (Group)

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Acknowledgements