interleukin 21
| UniProt | Protein Name |
|---|---|
| A0A224B028 |
|
| Q9HBE4 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of cytokine production | ||
| positive regulation of cytokine production | ||
| germinal center B cell differentiation | ||
| positive regulation of immunoglobulin production | ||
| signal transduction |
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytokine activity | ||
| cytokine receptor binding | ||
| interleukin-2 receptor binding | ||
| protein binding |
| Gene Ontology |
|---|
| cytokine activity |
| cytokine receptor binding |
| immune response |
| positive regulation of natural killer cell mediated cytotoxicity |
| InterPro |
|---|
| Four-helical cytokine-like, core |
| Interleukin-15/Interleukin-21 family |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0081153 | common variable immunodeficiency 11 | |
| DOID:2841 | asthma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:9074 | systemic lupus erythematosus |
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 59067 | Xenbase:XB-GENE-22201458 | ||
| 60505 | Xenbase:XB-GENE-22201458 | MOUSE37071 | |
| 365769 | Xenbase:XB-GENE-22201458 | RATNO22844 | |
| 378475 | BOVIN09223 | ||
| 403123 | PIGXX34167 | ||
| 442935 | CANLF06283 | ||
| 471295 | PANTR34433 | ||
| 708125 | MACMU37146 | ||
| 100063803 | HORSE28706 | ||
| 100223945 | TAEGU23697 |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: August 4, 2025