Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
Interleukin-21
Summary
- UniProt ID
- Q9HBE4
- Gene Symbol
- IL21
- Gene ID
- 59067
- Organism
- Homo sapiens (human)
Annotation
- Keyword
- 3D-structure Alternative splicing Cytokine Disease variant Disulfide bond Glycoprotein Proteomics identification Reference proteome Secreted Signal
Gene Ontology (GO)
| GO Term | Evidence Code | Reference |
|---|---|---|
| natural killer cell differentiation |
|
|
| positive regulation of cytokine production | ||
| positive regulation of cytokine production | ||
| positive regulation of cytokine production | ||
| germinal center B cell differentiation |
GO Hierarchy
- signal transduction
biological process
immune system process [inference]
cellular process [inference]
multicellular organismal process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of leukocyte activation [inference]
regulation of immune effector process [inference]
regulation of immune response [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of cellular process [inference]
positive regulation of metabolic process [inference]
positive regulation of cell activation [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of metabolic process [inference]
positive regulation of cell activation [inference]
regulation of cell activation [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
regulation of cell activation [inference]
positive regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | Reference |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| extracellular region | ||
| obsolete extracellular space |
|
|
| GO Term | Evidence Code | Reference |
|---|---|---|
| cytokine activity |
|
|
| cytokine receptor binding | ||
| cytokine receptor binding | ||
| interleukin-2 receptor binding |
GO Hierarchy
Sequence
MRSSPGNMERIVICLMVIFLGTLVHKSSSQGQDRHMIRMRQLIDIVDQLKNYVNDLVPEFLPAPEDVETNCEWSAFSCFQKAQLKSANTGNNERIINVSIKKLKRKPPSTNAGRRQKHRLTCPSCDSYEKKPPKEFLERFKSLLQKMIHQHLSSRTHGSEDS
Glycosylation Sites
| Position | Description | PubMed ID | GlyTouCan ID | Source |
|---|---|---|---|---|
| 97 |
|
|
Feature
: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt
Pathway
| Pathway Name | Organism |
|---|---|
| Interleukin-21 signaling | Homo sapiens |
Disease
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:9074 | systemic lupus erythematosus | |
| DOID:2841 | asthma | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:0081153 | common variable immunodeficiency 11 |
