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FAM3 metabolism regulating signaling molecule A

Summary

Gene Symbol

FAM3A

Organism

Homo sapiens (human)

External Links

NCBI Gene

60343

PubChem

60343

Alliance of Genome Resources

HGNC:13749

Annotation

Keyword

Alternative splicing
Disulfide bond
Lectin
Proteomics identification
Reference proteome
Secreted
Signal
Transmembrane helix

Proteins

Displaying **all 3** entries
UniProt	Protein Name
D3DWX8
P98173	Cytokine-like protein 2-19
Q9BU27

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
antifungal humoral response	IDA	18212107
antimicrobial humoral immune response mediated by antimicrobial peptide	IDA	18212107
negative regulation of antifungal innate immune response	IDA	18212107

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to fungus [inference]

defense response to fungus [inference]

antifungal humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to fungus [inference]

antifungal humoral response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to fungus [inference]

antifungal humoral response

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to fungus [inference]

defense response to fungus [inference]

antifungal humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to fungus [inference]

antifungal humoral response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to fungus [inference]

defense response to fungus [inference]

antifungal humoral response

defense response to other organism [inference]

antimicrobial humoral response [inference]

defense response to fungus [inference]

antifungal humoral response

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of antifungal innate immune response [inference]

negative regulation of antifungal innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

negative regulation of biological process [inference]

negative regulation of immune system process [inference]

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of response to stimulus [inference]

regulation of response to biotic stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of innate immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of antifungal innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of defense response to fungus [inference]

regulation of antifungal innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of response to external stimulus [inference]

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of innate immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of antifungal innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of defense response to fungus [inference]

regulation of antifungal innate immune response [inference]

negative regulation of antifungal innate immune response

negative regulation of response to stimulus [inference]

negative regulation of response to biotic stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

negative regulation of response to external stimulus [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of immune response [inference]

regulation of innate immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of antifungal innate immune response [inference]

negative regulation of antifungal innate immune response

negative regulation of immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of response to stress [inference]

regulation of defense response [inference]

negative regulation of defense response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of innate immune response [inference]

negative regulation of innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of antifungal innate immune response [inference]

negative regulation of antifungal innate immune response

regulation of defense response to fungus [inference]

regulation of antifungal innate immune response [inference]

negative regulation of antifungal innate immune response

Displaying 1 entry
GO Term	Evidence Code	PMID
extracellular space	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

Displaying 1 entry
GO Term	Evidence Code	PMID
carbohydrate binding	IEA

GO Hierarchy

molecular function

binding [inference]

carbohydrate binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Protein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
FAM3 family
ILEI/PANDER domain

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Caenorhabditis elegans	18300	WB:WBGene00019786
Caenorhabditis elegans	52793	WB:WBGene00019786
Caenorhabditis elegans	54097	WB:WBGene00019786
Xenopus tropicalis	60343	Xenbase:XB-GENE-968990
Mus musculus	66294		MOUSE65703
Caenorhabditis elegans	131177	WB:WBGene00019786
Danio rerio	177015	ZFIN:ZDB-GENE-040426-1772
Danio rerio	393773		DANRE51073
Pan troglodytes	465947		PANTR47154
Rattus norvegicus	501664		RATNO44526