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solute carrier family 25 member 19

Summary

Gene Symbol

SLC25A19

Organism

Homo sapiens (human)

External Links

NCBI Gene

60386

PubChem

60386

Alliance of Genome Resources

HGNC:14409

Annotation

Keyword

Alternative splicing
Antiport
Disease variant
Mitochondrion
Neuropathy
Phosphoprotein
Reference proteome
Repeat
Transmembrane
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q5JPC1	Solute carrier family 25 member 19
Q9HC21	Mitochondrial thiamine pyrophosphate transporter Mitochondrial uncoupling protein 1 Solute carrier family 25 member 19

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
thiamine diphosphate biosynthetic process	IEA
deoxynucleotide transport	NAS	11226231
deoxynucleotide transport	IDA	15539640
thiamine pyrophosphate transmembrane transport	IDA	17035501
thiamine pyrophosphate transmembrane transport	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organonitrogen compound metabolic process [inference]

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organonitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

heterocycle biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic cyclic compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organonitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

heterocycle biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

small molecule metabolic process [inference]

vitamin metabolic process [inference]

water-soluble vitamin metabolic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

small molecule biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic substance metabolic process [inference]

organophosphate metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic cyclic compound metabolic process [inference]

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic cyclic compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organonitrogen compound metabolic process [inference]

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organonitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic substance biosynthetic process [inference]

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organic cyclic compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

organonitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate metabolic process [inference]

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular biosynthetic process [inference]

vitamin biosynthetic process [inference]

water-soluble vitamin biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

heterocycle biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

aromatic compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

cellular nitrogen compound biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

sulfur compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

heterocycle metabolic process [inference]

heterocycle biosynthetic process [inference]

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound metabolic process [inference]

thiamine-containing compound metabolic process

thiamine diphosphate metabolic process [inference]

thiamine diphosphate biosynthetic process

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

thiamine-containing compound biosynthetic process [inference]

thiamine diphosphate biosynthetic process

transmembrane transport [inference]

vitamin transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

azole transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

pyrimidine-containing compound transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

localization [inference]

establishment of localization [inference]

transport [inference]

vitamin transport [inference]

thiamine transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

vitamin transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

transmembrane transport [inference]

vitamin transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

azole transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

pyrimidine-containing compound transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

organic substance transport [inference]

organic cation transport [inference]

thiamine transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

quaternary ammonium group transport [inference]

thiamine pyrophosphate transmembrane transport

organic anion transport [inference]

thiamine pyrophosphate transmembrane transport

organophosphate ester transport [inference]

nucleotide transport [inference]

deoxynucleotide transport

thiamine pyrophosphate transmembrane transport

nucleobase-containing compound transport [inference]

nucleotide transport [inference]

deoxynucleotide transport

azole transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

pyrimidine-containing compound transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

carbohydrate derivative transport [inference]

deoxynucleotide transport

nitrogen compound transport [inference]

quaternary ammonium group transport [inference]

thiamine pyrophosphate transmembrane transport

thiamine transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

nucleobase-containing compound transport [inference]

nucleotide transport [inference]

deoxynucleotide transport

azole transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

pyrimidine-containing compound transmembrane transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

sulfur compound transport [inference]

thiamine transport [inference]

thiamine transmembrane transport [inference]

thiamine pyrophosphate transmembrane transport

Displaying **all 5** entries
GO Term	Evidence Code	PMID
nucleus	HDA	21630459
mitochondrion	IDA	15539640 31506564
mitochondrion	HTP	34800366
mitochondrial inner membrane	TAS
mitochondrial inner membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
thiamine transmembrane transporter activity	IBA
antiporter activity	IEA
deoxynucleotide transmembrane transporter activity	TAS	11226231
deoxynucleotide transmembrane transporter activity	IDA	15539640 17035501
thiamine pyrophosphate transmembrane transporter activity	TAS

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic anion transmembrane transporter activity [inference]

thiamine pyrophosphate transmembrane transporter activity

organic cation transmembrane transporter activity [inference]

thiamine transmembrane transporter activity

thiamine pyrophosphate transmembrane transporter activity

quaternary ammonium group transmembrane transporter activity [inference]

thiamine pyrophosphate transmembrane transporter activity

organophosphate ester transmembrane transporter activity [inference]

nucleotide transmembrane transporter activity [inference]

deoxynucleotide transmembrane transporter activity

thiamine pyrophosphate transmembrane transporter activity

nucleobase-containing compound transmembrane transporter activity [inference]

nucleotide transmembrane transporter activity [inference]

deoxynucleotide transmembrane transporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

antiporter activity

vitamin transmembrane transporter activity [inference]

thiamine transmembrane transporter activity

thiamine pyrophosphate transmembrane transporter activity

azole transmembrane transporter activity [inference]

thiamine transmembrane transporter activity

thiamine pyrophosphate transmembrane transporter activity

sulfur compound transmembrane transporter activity [inference]

thiamine transmembrane transporter activity

thiamine pyrophosphate transmembrane transporter activity

salt transmembrane transporter activity [inference]

thiamine pyrophosphate transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Mitochondrial carrier

Functional Category

G: Carbohydrate transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
Mitochondrial carrier domain superfamily
Mitochondrial carrier protein
Mitochondrial substrate/solute carrier

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:10907	microcephaly	Alliance of Genome Resources
DOID:655	inherited metabolic disorder	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 77 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	60386	Xenbase:XB-GENE-5868233
Mus musculus	67283		MOUSE03203
Danio rerio	403024		DANRE32593
Pan troglodytes	454879		PANTR15413
Canis lupus familiaris	483311		CANLF18458
Bos taurus	504418		BOVIN13998
Macaca mulatta	706122		MACMU15610
Monodelphis domestica	100027430		MONDO10176
Ornithorhynchus anatinus	100075719		ORNAN00115
Pongo abelii	100174169		PONAB11590

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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External Links

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OrthoDB (Group)

International Collaboration

Acknowledgements