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UDP glucuronosyltransferase 1 family, polypeptide A8

Summary

Gene Symbol

Ugt1a8

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

613123

KEGG Gene ID

mmu:613123

PubChem

613123

Alliance of Genome Resources

MGI:3576090

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
liver development	IBA
cellular glucuronidation	IBA
coumarin catabolic process	ISO

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

secondary metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

cellular aromatic compound metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

aromatic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

heterocycle metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

small molecule metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

organic substance metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

organic cyclic compound metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

organic cyclic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

organic substance catabolic process [inference]

organic cyclic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular process [inference]

cellular metabolic process [inference]

organic acid metabolic process [inference]

oxoacid metabolic process [inference]

carboxylic acid metabolic process [inference]

monocarboxylic acid metabolic process [inference]

uronic acid metabolic process [inference]

glucuronate metabolic process [inference]

cellular glucuronidation

cellular aromatic compound metabolic process [inference]

phenylpropanoid metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

phenylpropanoid catabolic process [inference]

coumarin catabolic process

aromatic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

cellular catabolic process [inference]

aromatic compound catabolic process [inference]

phenylpropanoid catabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

heterocycle metabolic process [inference]

coumarin metabolic process [inference]

coumarin catabolic process

heterocycle catabolic process [inference]

coumarin catabolic process

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

gland development [inference]

liver development

Displaying 1 entry
GO Term	Evidence Code	PMID
endoplasmic reticulum	IBA ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
enzyme binding	IBA ISO
fatty acid binding	ISO
steroid binding	ISO
protein heterodimerization activity	ISO
retinoic acid binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

glucuronosyltransferase activity

hexosyltransferase activity [inference]

glucuronosyltransferase activity

binding [inference]

protein binding [inference]

kinase binding [inference]

protein kinase binding [inference]

protein kinase C binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

lipid binding [inference]

isoprenoid binding [inference]

retinoid binding [inference]

retinoic acid binding

small molecule binding [inference]

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

organic cyclic compound binding [inference]

steroid binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

UDP-glucuronosyltransferase 1-2 isoform X2

Functional Category

C: Energy production and conversion
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
UDP-glycosyltransferase activity
transferase activity

Displaying **all 2** entries
InterPro
UDP-glucuronosyl/UDP-glucosyltransferase
UDP-glycosyltransferase family, conserved site

KEGG BRITE Database

Orthology

K00699

Name

glucuronosyltransferase [EC:2.4.1.17]

References

Disease

Disease Ontology

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:1793	pancreatic cancer	Alliance of Genome Resources
DOID:4947	cholangiocarcinoma	Alliance of Genome Resources
DOID:4988	alcoholic pancreatitis	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of **118** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	53584		FB:FBgn0026755
Homo sapiens	54575		HGNC:12531	HUMAN67632
Homo sapiens	54576		HGNC:12540	HUMAN67631
Homo sapiens	54577		HGNC:12539	HUMAN67635
Homo sapiens	54600		HGNC:12541	HUMAN67634
Rattus norvegicus	113992	10116_1:003414		RATNO42391
Rattus norvegicus	154516	10116_1:0032c3		RATNO42391
Caenorhabditis elegans	175591		WB:WBGene00010904
Caenorhabditis elegans	178330		WB:WBGene00007455
Rattus norvegicus	301595	10116_1:003403	RGD:708474	RATNO42391

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024