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ribosomal protein L18

Summary

Gene Symbol

RPL18

Organism

Homo sapiens (human)

External Links

NCBI Gene

6141

PubChem

6141

Alliance of Genome Resources

HGNC:10310

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Diamond-Blackfan anemia
Direct protein sequencing
Disease variant
Endoplasmic reticulum
Isopeptide bond
Phosphoprotein
Reference proteome
Ribosomal protein
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
Q07020	60S ribosomal protein L18

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
translation	NAS	12962325
cytoplasmic translation	IC IDA NAS	23636399 25901680 25957688

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

amide metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

protein metabolic process [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

primary metabolic process [inference]

protein metabolic process [inference]

cytoplasmic translation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

protein metabolic process [inference]

cytoplasmic translation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

protein metabolic process [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
membrane	HDA	19946888
focal adhesion	HDA	21423176
cytosolic ribosome	IDA	23636399
endoplasmic reticulum	IDA
nucleus	HDA	21630459

GO Hierarchy

cellular component

protein-containing complex [inference]

ribonucleoprotein complex [inference]

ribosomal subunit [inference]

large ribosomal subunit [inference]

cytosolic large ribosomal subunit

cellular anatomical entity [inference]

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

endoplasmic reticulum

rough endoplasmic reticulum

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

ribosome [inference]

cytosolic ribosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

endoplasmic reticulum

rough endoplasmic reticulum

intracellular non-membrane-bounded organelle [inference]

nucleolus

ribosome [inference]

cytosolic ribosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	30021884 32814053 33961781 35271311
structural constituent of ribosome	IBA IDA NAS	12962325 23636399 32669547
RNA binding	IBA

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of ribosome

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

ribosomal protein

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
T: Signal transduction mechanisms

Displaying **all 3** entries
InterPro
Large ribosomal subunit protein eL18
Large ribosomal subunit protein uL15/eL18 superfamily
Large ribosomal subunit protein uL15/eL18

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0111896	Diamond-Blackfan anemia 18	Alliance of Genome Resources
DOID:1339	Diamond-Blackfan anemia	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 69 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Callithrix jacchus	100403300			CALJA24410
Pongo abelii	100443966	9601_0:004abf		PONAB15545
Ailuropoda melanoleuca	100479655			AILME14194
Oreochromis niloticus	100534549			ORENI08087
Nomascus leucogenys	100591658			NOMLE00355
Sus scrofa	100738912			PIGXX28188
Cricetulus griseus	100774500			CRIGR18249
Otolemur garnettii	100961389			OTOGA02161
Pan paniscus	100976561	9597_0:004dd2
Papio anubis	101013201			PAPAN22366

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024