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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
beta-secretase 1
Summary
- Gene Symbol
-
- BACE1
- Organism
- Bos taurus (domestic cattle)
Annotation
- Keyword
-
- Acetylation
- Aspartyl protease
- Cell membrane
- Cell projection
- Cytoplasmic vesicle
- Disulfide bond
- Endoplasmic reticulum
- Endosome
- Glycoprotein
- Golgi apparatus
- Isopeptide bond
- Lysosome
- Palmitate
- Phosphoprotein
- Reference proteome
- Signal
- Transmembrane helix
- Ubl conjugation
- Zymogen
- Proteins
| UniProt | Protein Name |
|---|---|
| Q2HJ40 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| proteolysis |
|
|
| membrane protein ectodomain proteolysis | ||
| amyloid-beta metabolic process |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytoplasmic vesicle membrane |
|
|
| plasma membrane |
|
|
| membrane raft |
|
|
| endosome | ||
| cell surface |
|
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| aspartic-type endopeptidase activity | ||
| endopeptidase activity |
|
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- aspartic
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| aspartic-type endopeptidase activity |
| proteolysis |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 23621 | HUMAN09577 | |||
| 23821 | MOUSE63151 | |||
| 29392 | RATNO39964 | |||
| 451573 | PANTR04425 | |||
| 697694 | MACMU09930 | |||
| 100025518 | MONDO25208 | |||
| 100071137 | HORSE39158 | |||
| 100079669 | ORNAN02614 | |||
| 100135485 | CAVPO10180 | |||
| 100343442 | RABIT00578 |
