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glycogen phosphorylase L

Summary

Gene Symbol

Pygl

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

64035

KEGG Gene ID

PubChem

64035

Alliance of Genome Resources

RGD:620687

Annotation

Keyword

Acetylation
Allosteric enzyme
Cytoplasm
Glycogen metabolism
Glycosyltransferase
Nucleotide-binding
Phosphoprotein
Pyridoxal phosphate
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6HBY8
P09811

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
carbohydrate metabolic process	IEA
glycogen metabolic process	ISO
glycogen metabolic process	IDA
glycogen catabolic process	ISO
glycogen catabolic process	IDA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

generation of precursor metabolites and energy [inference]

energy derivation by oxidation of organic compounds [inference]

energy reserve metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

phosphorus metabolic process [inference]

organophosphate metabolic process [inference]

ribose phosphate metabolic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

5-phosphoribose 1-diphosphate metabolic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

organophosphate biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

catabolic process [inference]

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

biosynthetic process [inference]

organophosphate biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

macromolecule metabolic process [inference]

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

macromolecule catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

primary metabolic process [inference]

carbohydrate metabolic process

polysaccharide metabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

glucan metabolic process [inference]

glycogen metabolic process

glycogen catabolic process

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate catabolic process [inference]

polysaccharide catabolic process [inference]

glucan catabolic process [inference]

glycogen catabolic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

5-phosphoribose 1-diphosphate metabolic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

carbohydrate derivative biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

5-phosphoribose 1-diphosphate biosynthetic process

cell death [inference]

programmed cell death [inference]

programmed necrotic cell death [inference]

necroptotic process

homeostatic process [inference]

chemical homeostasis [inference]

carbohydrate homeostasis [inference]

glucose homeostasis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytoplasm
cytosol	IBA
cytosol	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

Displaying entries **11 - 15** of 17 in total

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GO Term	Evidence Code	PMID
vitamin binding	ISO
pyridoxal phosphate binding	IEA
carbohydrate binding	IDA
carbohydrate binding	IEA
bile acid binding	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

hexosyltransferase activity [inference]

1,4-alpha-oligoglucan phosphorylase activity

glycogen phosphorylase activity

binding [inference]

protein binding [inference]

identical protein binding

carbohydrate binding

monosaccharide binding [inference]

D-glucose binding

small molecule binding [inference]

vitamin binding

vitamin B6 binding [inference]

pyridoxal phosphate binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

bile acid binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

cation binding [inference]

AMP binding

organic acid binding [inference]

carboxylic acid binding [inference]

monocarboxylic acid binding [inference]

bile acid binding

monosaccharide binding [inference]

D-glucose binding

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

nucleobase binding [inference]

purine nucleobase binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

vitamin B6 binding [inference]

pyridoxal phosphate binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:41732

phosphate

α-D-glucose 1-phosphate

Enzyme

2.4.1.1

PMID

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:2754	glycogen storage disease VI	Alliance of Genome Resources
DOID:3650	lactic acidosis	Alliance of Genome Resources

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	5836	HGNC:9725
Saccharomyces cerevisiae S288C	856289	SGD:S000006364
Mus musculus	110095	MGI:97829
Drosophila melanogaster	33386	FB:FBgn0004507

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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