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roundabout guidance receptor 3

Summary

Gene Symbol

ROBO3

Organism

Homo sapiens (human)

External Links

NCBI Gene

64221

PubChem

64221

Alliance of Genome Resources

HGNC:13433

Annotation

Keyword

3D-structure
Alternative splicing
Chemotaxis
Developmental protein
Differentiation
Disease variant
Disulfide bond
Glycoprotein
Immunoglobulin domain
Neurogenesis
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q96MS0	Roundabout-like protein 3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
chemotaxis	IEA
positive regulation of axon guidance	IEA
dendrite self-avoidance	IBA
axon midline choice point recognition	ISS
homophilic cell adhesion via plasma membrane adhesion molecules	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

cell recognition [inference]

neuron recognition [inference]

axon choice point recognition [inference]

axon midline choice point recognition

dendrite self-avoidance

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

locomotion [inference]

taxis [inference]

chemotaxis

biological regulation [inference]

regulation of biological process [inference]

regulation of locomotion [inference]

regulation of chemotaxis [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

regulation of response to stimulus [inference]

regulation of response to external stimulus [inference]

regulation of chemotaxis [inference]

regulation of axon guidance [inference]

positive regulation of axon guidance

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

regulation of axon guidance [inference]

positive regulation of axon guidance

positive regulation of cellular component organization [inference]

positive regulation of cell projection organization [inference]

positive regulation of neuron projection development [inference]

positive regulation of axon guidance

Displaying **all 3** entries
GO Term	Evidence Code	PMID
membrane	NAS	15105459
plasma membrane	IBA TAS
axon	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	26586761 32198364
cell-cell adhesion mediator activity	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

cell adhesion molecule binding [inference]

cell adhesion mediator activity [inference]

cell-cell adhesion mediator activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

roundabout

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 6** entries
InterPro
Immunoglobulin I-set
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060475	myoclonic-atonic epilepsy	Alliance of Genome Resources

Ortholog

Displaying entries **11 - 20** of 47 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Oryctolagus cuniculus	100342258			RABIT00491
Callithrix jacchus	100403106			CALJA05527
Ailuropoda melanoleuca	100469109			AILME07912
Xenopus tropicalis	100493553		Xenbase:XB-GENE-1032334
Nomascus leucogenys	100588193			NOMLE10010
Cavia porcellus	100721535			CAVPO10092
Sarcophilus harrisii	100920803			SARHA04868
Otolemur garnettii	100947905			OTOGA06014
Pan paniscus	100988814	9597_0:002dd3		PANPA08240
Papio anubis	101014013			PAPAN04943

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements