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G protein-coupled receptor 89A

Summary

Gene Symbol

GPR89A

Organism

Homo sapiens (human)

External Links

NCBI Gene

653519

PubChem

653519

Alliance of Genome Resources

HGNC:31984

Annotation

Keyword

Alternative splicing
Glycoprotein
Golgi apparatus
Protein transport
Receptor
Reference proteome
Transmembrane helix
Voltage-gated channel

Proteins

Displaying **all 3** entries
UniProt	Protein Name
B7ZAQ6	Protein GPR89A Putative MAPK-activating protein PM01 Putative NF-kappa-B-activating protein 90
X5D7G6
P0CG08	Protein GPR89B

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein transport	IEA
T cell differentiation	ISS
positive regulation of canonical NF-kappaB signal transduction	HMP	12761501
intracellular pH reduction	IDA	18794847
intracellular pH reduction	IBA

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation

T cell activation [inference]

T cell differentiation

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation

T cell activation [inference]

T cell differentiation

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

lymphocyte activation [inference]

lymphocyte differentiation [inference]

T cell differentiation

T cell activation [inference]

T cell differentiation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

T cell differentiation

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction

monoatomic cation homeostasis [inference]

regulation of pH [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic anion transport [inference]

monoatomic anion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic anion transmembrane transport

organic substance transport [inference]

protein transport

nitrogen compound transport [inference]

protein transport

establishment of protein localization [inference]

protein transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of pH [inference]

regulation of cellular pH [inference]

regulation of intracellular pH [inference]

intracellular pH reduction

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of intracellular signal transduction [inference]

regulation of canonical NF-kappaB signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of canonical NF-kappaB signal transduction

regulation of biological quality [inference]

regulation of intracellular pH [inference]

intracellular pH reduction

Displaying **all 5** entries
GO Term	Evidence Code	PMID
Golgi membrane	IEA
Golgi-associated vesicle membrane	IDA	18794847
Golgi cisterna membrane	IDA	18794847
Golgi cisterna membrane	IBA
monoatomic ion channel complex	IEA

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

Golgi-associated vesicle membrane

Golgi cisterna membrane

bounding membrane of organelle [inference]

Displaying **all 2** entries
GO Term	Evidence Code	PMID
voltage-gated monoatomic anion channel activity	IDA	18794847
voltage-gated monoatomic anion channel activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic anion channel activity

monoatomic anion channel activity [inference]

voltage-gated monoatomic anion channel activity

monoatomic anion transmembrane transporter activity [inference]

monoatomic anion channel activity [inference]

voltage-gated monoatomic anion channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic anion channel activity

monoatomic anion channel activity [inference]

voltage-gated monoatomic anion channel activity

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic anion channel activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Golgi pH regulator

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
abscisic acid binding
intracellular pH reduction
response to abscisic acid

Displaying **all 3** entries
InterPro
Abscisic acid G-protein coupled receptor-like domain
Golgi pH regulator, conserved domain
The Golgi pH regulator/GPCR-type G protein

Ortholog

Displaying entries **1 - 10** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	51463	Xenbase:XB-GENE-484935
Mus musculus	67549	Xenbase:XB-GENE-484935	MOUSE37617
Rattus norvegicus	362003		RATNO22824
Xenopus tropicalis	446579	Xenbase:XB-GENE-484935
Pan troglodytes	457978		PANTR21811
Canis lupus familiaris	483157		CANLF05332
Xenopus tropicalis	653519	Xenbase:XB-GENE-484935
Macaca mulatta	696579		MACMU22103
Bos taurus	767859		BOVIN26099
Monodelphis domestica	100014708		MONDO14800