Submissions
GlyTouCan
Glycan Structure Repository
GlyComb
Glycoconjugate Repository
GlycoPOST
Glycomics MS raw data Repository
UniCarb-DR
Glycomics MS Repository for glycan annotations from GlycoWorkbench
LM-GlycoRepo
Repository for lectin-assisted multimodality data
All Resources
Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / OrganismsTools
SugarDrawer
GlycanBuilder
Glycan Converters
GlycoMaple
GlycomeAtlas
LM-GlycomeAtlas
GALAXY
MCAW
GlycoSim
GRable
Guidelines
MIRAGE
solute carrier family 18 member A3
Summary
- Gene Symbol
-
- SLC18A3
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- Congenital myasthenic syndrome
- Cytoplasmic vesicle
- Disease variant
- Glycoprotein
- Neurotransmitter transport
- Reference proteome
- Synapse
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q16572 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| neurotransmitter transport | ||
| chemical synaptic transmission | ||
| positive regulation of acetylcholine secretion, neurotransmission | ||
| serotonin uptake | ||
| acetylcholine uptake |
GO Hierarchy
biological process
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
positive regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| AP-1 adaptor complex | ||
| AP-2 adaptor complex | ||
| clathrin-coated endocytic vesicle membrane | ||
| synaptic vesicle membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| acetylcholine transmembrane transporter activity | ||
| acetylcholine transmembrane transporter activity | ||
| acetylcholine:proton antiporter activity | ||
| protein binding | ||
| monoamine:proton antiporter activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- vesicular acetylcholine transporter
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- Q: Secondary metabolites biosynthesis, transport and catabolism
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| aminergic neurotransmitter loading into synaptic vesicle |
| InterPro |
|---|
| MFS transporter superfamily |
| Major facilitator superfamily domain |
| Major facilitator superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110672 | congenital myasthenic syndrome 21 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 6572 | Xenbase:XB-GENE-965085 | ||
| 20508 | MOUSE13886 | ||
| 42795 | Xenbase:XB-GENE-965085 | ||
| 60422 | Xenbase:XB-GENE-965085 | ||
| 394082 | Xenbase:XB-GENE-965085 | ||
| 445809 | CIOIN00637 | ||
| 466071 | PANTR00598 | ||
| 486774 | CANLF11255 | ||
| 559347 | Xenbase:XB-GENE-965085 | ||
| 710053 | MACMU44800 |
