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phospholipase B1

Summary

Gene Symbol

Plb1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

665270

KEGG Gene ID

PubChem

665270

Alliance of Genome Resources

MGI:1922406

Annotation

Keyword

Alternative splicing
Cell membrane
Glycoprotein
Hydrolase
Phospholipid metabolism
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q3TTY0	Lysophospholipase Phospholipase A2 Phospholipase B/lipase Triacylglycerol lipase
Q8K255

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
lipid metabolic process	IEA
phospholipid metabolic process	ISO
phospholipid metabolic process	IBA
phospholipid metabolic process	IEA
triglyceride catabolic process	ISO

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

organophosphate metabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol catabolic process

glycerophospholipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

catabolic process [inference]

lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

organophosphate catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

hormone metabolic process [inference]

retinol metabolic process

primary metabolic process [inference]

lipid metabolic process

neutral lipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride catabolic process

diacylglycerol metabolic process [inference]

diacylglycerol catabolic process

acylglycerol catabolic process [inference]

neutral lipid catabolic process [inference]

acylglycerol catabolic process [inference]

phospholipid metabolic process

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol catabolic process

glycerophospholipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

isoprenoid metabolic process [inference]

terpenoid metabolic process [inference]

diterpenoid metabolic process [inference]

retinoid metabolic process [inference]

retinol metabolic process

lipid catabolic process [inference]

phospholipid catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

glycerolipid metabolic process [inference]

acylglycerol metabolic process [inference]

triglyceride metabolic process [inference]

triglyceride catabolic process

diacylglycerol metabolic process [inference]

diacylglycerol catabolic process

acylglycerol catabolic process [inference]

glycerophospholipid metabolic process [inference]

phosphatidylethanolamine metabolic process [inference]

phosphatidylethanolamine catabolic process

phosphatidylcholine metabolic process [inference]

phosphatidylcholine catabolic process

phosphatidylglycerol metabolic process [inference]

phosphatidylglycerol catabolic process

glycerophospholipid catabolic process [inference]

glycerolipid catabolic process [inference]

acylglycerol catabolic process [inference]

glycerophospholipid catabolic process [inference]

small molecule metabolic process [inference]

alcohol metabolic process [inference]

primary alcohol metabolic process [inference]

retinol metabolic process

olefinic compound metabolic process [inference]

retinol metabolic process

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of reproductive process [inference]

positive regulation of acrosome reaction

regulation of reproductive process [inference]

regulation of acrosome reaction [inference]

positive regulation of acrosome reaction

positive regulation of reproductive process [inference]

positive regulation of acrosome reaction

regulation of biological quality [inference]

regulation of hormone levels [inference]

hormone metabolic process [inference]

retinol metabolic process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
apical plasma membrane	IEA
brush border membrane	ISO
brush border membrane	IBA
brush border membrane	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

Displaying entries **1 - 5** of 18 in total

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GO Term	Evidence Code	PMID
glycerophospholipase activity	IEA
phosphatidylcholine lysophospholipase A1 activity	ISS
phosphatidylcholine lysophospholipase A1 activity	ISO
phosphatidylcholine lysophospholipase A1 activity	IBA
phosphatidylcholine lysophospholipase A1 activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds

lipase activity

triacylglycerol lipase activity

phospholipase activity [inference]

glycerophospholipase activity

A2-type glycerophospholipase activity

A1-type glycerophospholipase activity [inference]

lysophospholipase A1 activity [inference]

phosphatidylcholine lysophospholipase A1 activity

carboxylic ester hydrolase activity [inference]

A1-type glycerophospholipase activity [inference]

lysophospholipase A1 activity [inference]

phosphatidylcholine lysophospholipase A1 activity

Gene Ontology information from NCBI Gene and UniProt.

Rhea

RHEA:15177

H₂O + a 1-acyl-sn-glycero-3-phosphocholine

H⁺ + sn-glycerol 3-phosphocholine + a fatty acid

Enzyme

3.1.1.5

PMID

RHEA:15801

H₂O + a 1,2-diacyl-sn-glycero-3-phosphocholine

H⁺ + a fatty acid + a 1-acyl-sn-glycero-3-phosphocholine

Enzyme

3.1.1.4

PMID

RHEA:12044

H₂O + a triacylglycerol

H⁺ + a diacylglycerol + a fatty acid

Enzyme

PMID

RHEA:36231

H₂O + 1-O-alkyl-2-acyl-sn-glycero-3-phosphocholine

H⁺ + a fatty acid + 1-O-alkyl-sn-glycero-3-phosphocholine

Enzyme

3.1.1.4

PMID

9442064

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	151056	HGNC:30041
Rattus norvegicus	192259	RGD:621565
Caenorhabditis elegans	174746	WB:WBGene00012201
Caenorhabditis elegans	181691	WB:WBGene00008621