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Guidelines

MIRAGE

autophagy related 4B, cysteine peptidase

Summary

Gene Symbol

Atg4b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

66615

KEGG Gene ID

PubChem

66615

Alliance of Genome Resources

MGI:1913865

Annotation

Keyword

Acetylation
Autophagy
Cytoplasm
Cytoplasmic vesicle
Disulfide bond
Endoplasmic reticulum
Glycoprotein
Isopeptide bond
Mitochondrion
Phosphoprotein
Protein transport
Proteomics identification
Reference proteome
S-nitrosylation
Thiol protease
Ubl conjugation
Ubl conjugation pathway

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8BGE6	AUT-like 1 cysteine endopeptidase Autophagy-related cysteine endopeptidase 1 Autophagy-related protein 4 homolog B
A0A0R4J065

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 26 in total

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GO Term	Evidence Code	PMID
autophagosome assembly	ISO
autophagosome assembly	IMP
autophagosome assembly	IBA
mitophagy	ISS
mitophagy	ISO

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

catabolic process [inference]

autophagy of mitochondrion [inference]

mitophagy

macroautophagy [inference]

nucleophagy [inference]

piecemeal microautophagy of the nucleus

piecemeal microautophagy of the nucleus

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein processing

protein modification process [inference]

protein delipidation

protein maturation [inference]

protein processing

macromolecule modification [inference]

protein modification process [inference]

protein delipidation

primary metabolic process [inference]

protein metabolic process [inference]

protein processing

protein modification process [inference]

protein delipidation

protein maturation [inference]

protein processing

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

process utilizing autophagic mechanism [inference]

autophagy of mitochondrion [inference]

mitophagy

macroautophagy [inference]

nucleophagy [inference]

piecemeal microautophagy of the nucleus

piecemeal microautophagy of the nucleus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vacuole organization [inference]

autophagosome organization [inference]

autophagosome assembly

organelle assembly [inference]

autophagosome assembly

cellular component assembly [inference]

organelle assembly [inference]

autophagosome assembly

developmental process [inference]

anatomical structure development [inference]

animal gross anatomical part developmental process [inference]

tissue development [inference]

biomineral tissue development [inference]

otolith mineralization [inference]

otolith mineralization completed early in development

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

localization [inference]

macromolecule localization [inference]

intracellular protein localization [inference]

establishment of localization [inference]

transport [inference]

protein transport

establishment of protein localization [inference]

protein transport

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of cellular process [inference]

regulation of metabolic process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of catabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

regulation of primary metabolic process [inference]

regulation of protein metabolic process [inference]

regulation of protein catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

positive regulation of cellular process [inference]

positive regulation of metabolic process [inference]

positive regulation of catabolic process [inference]

positive regulation of protein catabolic process

positive regulation of macromolecule metabolic process [inference]

positive regulation of protein metabolic process [inference]

positive regulation of protein catabolic process

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
autophagosome membrane	ISO
autophagosome membrane	IEA
cytoplasm	ISO
cytoplasm	IDA
cytoplasm	IBA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

membrane [inference]

organelle membrane [inference]

bounding membrane of organelle [inference]

vacuolar membrane [inference]

autophagosome membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

mitochondrion

vacuole [inference]

autophagosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

vacuole [inference]

autophagosome

endoplasmic reticulum

intracellular vesicle [inference]

cytoplasmic vesicle

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
endopeptidase activity	ISO
cysteine-type endopeptidase activity	ISO
cysteine-type endopeptidase activity	IBA
cysteine-type endopeptidase activity	IEA
protein binding	IPI

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity

endopeptidase activity

cysteine-type endopeptidase activity

cysteine-type peptidase activity

cysteine-type endopeptidase activity

protein-phosphatidylethanolamide deconjugating activity

catalytic activity, acting on a protein [inference]

peptidase activity

endopeptidase activity

cysteine-type endopeptidase activity

cysteine-type peptidase activity

cysteine-type endopeptidase activity

protein-phosphatidylethanolamide deconjugating activity

binding [inference]

protein binding

scaffold protein binding

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying 1 entry
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	23192	HGNC:20790

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026