BRCA1 DNA repair associated

Summary
Gene Symbol
  • BRCA1
Organism
Homo sapiens (human)
NCBI Gene
672
PubChem
672
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Activator
  • Alternative initiation
  • Alternative splicing
  • Cell cycle
  • Chromosome
  • Coiled coil
  • Cytoplasm
  • DNA recombination
  • DNA repair
  • DNA-binding
  • Direct protein sequencing
  • Disease variant
  • Fanconi anemia
  • Fatty acid biosynthesis
  • Isopeptide bond
  • Nucleus
  • Phosphoprotein
  • Reference proteome
  • Repeat
  • Transcription regulation
  • Transferase
  • Tumor suppressor
  • Ubl conjugation
  • Ubl conjugation pathway
  • Zinc-finger
Proteins
Displaying all 2 entries
UniProt Protein Name
P38398
  • RING finger protein 53
  • RING-type E3 ubiquitin transferase BRCA1
A0A9Y1QQK3
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
E3 ubiquitin ligase
Functional Category
  • K: Transcription
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying 1 entry
Gene Ontology
metal ion binding
Disease
Disease Ontology
Displaying entries 11 - 17 of 17 in total
DO ID Disease Name Source
DOID:3748 esophagus squamous cell carcinoma
DOID:3908 lung non-small cell carcinoma
DOID:4362 cervical cancer
DOID:5683 hereditary breast ovarian cancer syndrome
DOID:8991 cervix uteri carcinoma in situ
DOID:9256 colorectal cancer
DOID:9261 nasopharynx carcinoma

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: April 7, 2025