hereditary breast ovarian cancer syndrome

Summary
Synonym
  • BRCA1- and BRCA2-associated hereditary breast and ovarian cancer
  • Breast and Ovarian Cancer syndrome
  • HBOC syndrome
  • Hereditary Breast and Ovarian Cancer syndrome
  • Hereditary breast and ovarian cancer
Definition
A syndrome characterized by the higher than normal tendency associated with BRCA1 and BRCA2 to develop breast and ovarian cancers in genetically related families.
Super Class
autosomal dominant disease syndrome
Disease Ontology
DOID:5683
Mondo Disease Ontology
MeSH
UMLS
NCI Thesaurus
MGI genotype (from TogoID)
Related Genes
Displaying all 4 entries
Gene ID Gene Symbol Description Source
672 BRCA1 BRCA1 DNA repair associated
675 BRCA2 BRCA2 DNA repair associated
5889 RAD51C RAD51 paralog C
79728 PALB2 partner and localizer of BRCA2

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 9, 2024