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potassium voltage-gated channel subfamily C member 4

Summary

Gene Symbol

Kcnc4

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

684516

PubChem

684516

Alliance of Genome Resources

RGD:1589169

Annotation

Keyword

Glycoprotein
Metal-binding
Phosphoprotein
Potassium channel
Reference proteome
Transmembrane helix
Voltage-gated channel
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
Q63734	Potassium voltage-gated channel subfamily C member 4 Raw3 Voltage-gated potassium channel subunit Kv3.4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
action potential	IBA
optic nerve development	IEP	22473424
cerebral cortex development	IEP	22473424
corpus callosum development	IEP	22473424
forebrain development	IEP	22473424

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

axon development

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

protein homooligomerization

developmental process [inference]

anatomical structure development [inference]

nerve development [inference]

cranial nerve development [inference]

optic nerve development

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

potassium ion transport [inference]

potassium ion transmembrane transport

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

transmembrane transport [inference]

monoatomic ion transmembrane transport [inference]

monoatomic cation transmembrane transport [inference]

potassium ion transmembrane transport

inorganic ion transmembrane transport [inference]

inorganic cation transmembrane transport [inference]

potassium ion transmembrane transport

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

regulation of localization [inference]

regulation of transport [inference]

regulation of secretion [inference]

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion

regulation of neurotransmitter transport [inference]

regulation of neurotransmitter secretion

negative regulation of biological process [inference]

negative regulation of action potential [inference]

negative regulation of neuronal action potential

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of cellular process [inference]

regulation of cell communication [inference]

negative regulation of cell communication [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of transmission of nerve impulse [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of neuronal action potential [inference]

negative regulation of neuronal action potential

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of neurotransmitter secretion

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of secretion by cell [inference]

regulation of neurotransmitter secretion

regulation of multicellular organismal process [inference]

regulation of system process [inference]

regulation of nervous system process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of transmission of nerve impulse [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of neuronal action potential [inference]

negative regulation of neuronal action potential

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system process [inference]

negative regulation of transmission of nerve impulse [inference]

negative regulation of neuronal action potential

regulation of action potential [inference]

negative regulation of action potential [inference]

negative regulation of neuronal action potential

regulation of neuronal action potential [inference]

negative regulation of neuronal action potential

regulation of biological quality [inference]

regulation of membrane potential [inference]

regulation of action potential [inference]

negative regulation of action potential [inference]

negative regulation of neuronal action potential

regulation of neuronal action potential [inference]

negative regulation of neuronal action potential

regulation of presynaptic membrane potential

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
synaptic vesicle	IDA	15207333
voltage-gated potassium channel complex	IBA
voltage-gated potassium channel complex	IEA
cell surface	IDA	21943416
axon	IDA	22473424

GO Hierarchy

cellular component

protein-containing complex [inference]

membrane protein complex [inference]

plasma membrane protein complex [inference]

voltage-gated potassium channel complex

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

transporter complex [inference]

transmembrane transporter complex [inference]

monoatomic ion channel complex [inference]

cation channel complex [inference]

potassium channel complex [inference]

voltage-gated potassium channel complex

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane region [inference]

cell projection membrane [inference]

neuron projection membrane [inference]

dendrite membrane

synaptic membrane [inference]

cell junction [inference]

synapse [inference]

leading edge membrane [inference]

neuron projection membrane [inference]

dendrite membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

transport vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

secretory vesicle [inference]

exocytic vesicle [inference]

synaptic vesicle

cell body [inference]

neuronal cell body

cell body membrane [inference]

neuronal cell body membrane

neuron projection terminus [inference]

axon terminus

calyx of Held

presynapse [inference]

axon terminus

calyx of Held

postsynapse

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
voltage-gated potassium channel activity	ISO
voltage-gated potassium channel activity	IDA	1840526
voltage-gated potassium channel activity	IEA
delayed rectifier potassium channel activity	IBA
protein binding	IPI	21943417

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

monoatomic ion transmembrane transporter activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

monoatomic cation transmembrane transporter activity [inference]

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

passive transmembrane transporter activity [inference]

channel activity [inference]

monoatomic ion channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

monoatomic cation channel activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

gated channel activity [inference]

voltage-gated channel activity [inference]

voltage-gated monoatomic ion channel activity [inference]

voltage-gated monoatomic cation channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

salt transmembrane transporter activity [inference]

potassium ion transmembrane transporter activity [inference]

potassium channel activity [inference]

voltage-gated potassium channel activity

delayed rectifier potassium channel activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Potassium channel

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 6** entries
Gene Ontology
delayed rectifier potassium channel activity
monoatomic ion channel activity
monoatomic ion transport
potassium channel activity
protein homooligomerization
voltage-gated potassium channel activity

Displaying **all 6** entries
InterPro
BTB/POZ domain
Ion transport domain
Potassium channel tetramerisation-type BTB domain
Potassium channel, voltage dependent, Kv
SKP1/BTB/POZ domain superfamily
Voltage-dependent channel domain superfamily

Alliance of Genome Resources

Expression

Displaying **all 6** entries
Location	References
cell surface	PMID:21943416
axon	PMID:22473424
postsynapse	PMID:15207333
neuronal cell body	PMID:15207333 PMID:22473424
synaptic vesicle	PMID:15207333
dendrite	PMID:15207333

Ortholog

Displaying entries **21 - 30** of 67 in total

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Species	Gene ID	Orthologous MAtrix
Callithrix jacchus	100409517	CALJA42007
Pongo abelii	100447867	PONAB17207
Meleagris gallopavo	100540617	MELGA08269
Anolis carolinensis	100563924	ANOCA06134
Nomascus leucogenys	100592102	NOMLE05369
Loxodonta africana	100672323	LOXAF15294
Cavia porcellus	100734488	CAVPO01467
Otolemur garnettii	100940574	OTOGA16617
Papio anubis	101019909	PAPAN20560
Felis catus	101081563	FELCA19361

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OrthoDB (Group)

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