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thromboxane A2 receptor
Summary
- Gene Symbol
-
- TBXA2R
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Cell membrane
- Direct protein sequencing
- Disease variant
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Phosphoprotein
- Reference proteome
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| smooth muscle contraction | ||
| inflammatory response | ||
| G protein-coupled receptor signaling pathway | ||
| adenylate cyclase-activating G protein-coupled receptor signaling pathway | ||
| positive regulation of cytosolic calcium ion concentration |
GO Hierarchy
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| acrosomal vesicle | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane | ||
| nuclear speck |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| thromboxane A2 receptor activity | ||
| guanyl-nucleotide exchange factor activity | ||
| protein binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- thromboxane A2 receptor
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- L: Replication, recombination and repair
- T: Signal transduction mechanisms
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
| Prostanoid receptor |
| Thromboxane receptor |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080822 | aspirin-induced respiratory disease | |
| DOID:2218 | blood platelet disease | |
| DOID:2841 | asthma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 19217 | FB:FBgn0036742 | ||
| 19219 | FB:FBgn0036742 | ||
| 19220 | FB:FBgn0036742 | ||
| 19222 | FB:FBgn0036742 | ||
| 21390 | Xenbase:XB-GENE-996433 | MOUSE02936 | |
| 24816 | Xenbase:XB-GENE-996433 | RATNO37728 | |
| 24929 | FB:FBgn0036742 | ||
| 25637 | FB:FBgn0036742 | ||
| 25652 | FB:FBgn0036742 | ||
| 63889 | FB:FBgn0036742 |
