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Thromboxane A2 receptor

Summary

UniProt ID

P21731

Gene Symbol

TBXA2R

Gene ID

6915

Organism

Homo sapiens (human)

External Links

GlyGen: P21731
PubChem: P21731
The Human Metabolome Database: HMDBP02023
RaftProt: P21731
Re-Glyco: P21731

Annotation

Keyword

3D-structure
Alternative splicing
Cell membrane
Direct protein sequencing
Disease variant
Disulfide bond
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Transmembrane helix

Gene Ontology (GO)

Displaying **all 3** entries
GO Term
nuclear speck
plasma membrane
acrosomal vesicle

Subcellular Location(GO Annotation)

Subcellular in which this glycoprotein is expressed are highlighted in blue.

Displaying entries **1 - 10** of 16 in total

1

2

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GO Term
positive regulation of blood pressure
adenylate cyclase-activating G protein-coupled receptor signaling pathway
positive regulation of cytosolic calcium ion concentration
response to nutrient
response to xenobiotic stimulus
response to testosterone
response to ethanol
cellular response to lipopolysaccharide
positive regulation of vasoconstriction
smooth muscle contraction

Displaying **all 2** entries
GO Term
thromboxane A2 receptor activity
guanyl-nucleotide exchange factor activity

Annotation information from UniProt.

Sequence

MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ

N : N-glycosylation Site
___ : Potential Sequon

Glycosylation Sites

Displaying **all 2** entries
Position	Description	PubMed ID	GlyTouCan ID	Source
4				UniProt GlyGen
16			G80920RR	UniProt GlyGen

Feature

: Glycosylation Site from GlyGen
: Glycosylation Site from UniProt

Pathway

Displaying **all 4** entries
Pathway Name	Organism
G alpha (12/13) signalling events	Homo sapiens
G alpha (q) signalling events	Homo sapiens
Prostanoid ligand receptors	Homo sapiens
Thromboxane signalling through TP receptor	Homo sapiens

Disease

Displaying **all 3** entries
DO ID	Disease Name	Source
DOID:0080822	aspirin-induced respiratory disease	Alliance of Genome Resources
DOID:2218	blood platelet disease	Alliance of Genome Resources
DOID:2841	asthma	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

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Summary

External Links

Annotation

International Collaboration

Acknowledgements