GlyCosmos Portal

Displaying entries **1 - 5** of 25 in total

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GO Term	Evidence Code	PMID
telomerase catalytic core complex	NAS	20351177
telomerase catalytic core complex	IDA	16507993 17940095 18082603 9398860 9443919
telomerase catalytic core complex	IMP	11313459
telomerase catalytic core complex	IBA
telomerase catalytic core complex	IPI	19701182

GO Hierarchy

cellular component

protein-containing complex [inference]

protein-DNA complex [inference]

telomere cap complex [inference]

nuclear telomere cap complex

nuclear protein-containing complex [inference]

nuclear telomere cap complex

telomerase holoenzyme complex

telomerase catalytic core complex

intracellular protein-containing complex [inference]

RNA polymerase complex [inference]

RNA-directed RNA polymerase complex

TERT-RMRP complex

catalytic complex [inference]

telomerase holoenzyme complex

telomerase catalytic core complex

transferase complex [inference]

transferase complex, transferring phosphorus-containing groups [inference]

telomerase catalytic core complex

RNA polymerase complex [inference]

RNA-directed RNA polymerase complex

TERT-RMRP complex

ribonucleoprotein complex [inference]

telomerase holoenzyme complex

telomerase catalytic core complex

TERT-RMRP complex

cellular anatomical entity [inference]

nucleoid [inference]

mitochondrial nucleoid

membrane [inference]

plasma membrane

nuclear body [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

chromosomal region [inference]

chromosome, telomeric region

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
tRNA binding	IDA	21937513
transcription coactivator binding	IPI	19571879
DNA binding	IDA	21937513
telomerase activity	TAS	11927518 14991929 23474713 23784080
telomerase activity	IDA	12135483 16043710 16507993 17940095 18082603 21531765 29695869 9398860 9443919

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

DNA polymerase activity [inference]

RNA-directed DNA polymerase activity

telomerase activity

RNA polymerase activity [inference]

5'-3' RNA polymerase activity [inference]

RNA-dependent RNA polymerase activity

template-free RNA nucleotidyltransferase

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on DNA [inference]

DNA polymerase activity [inference]

RNA-directed DNA polymerase activity

telomerase activity

catalytic activity, acting on RNA [inference]

RNA polymerase activity [inference]

5'-3' RNA polymerase activity [inference]

RNA-dependent RNA polymerase activity

template-free RNA nucleotidyltransferase

binding [inference]

protein binding

transcription factor binding [inference]

transcription coregulator binding [inference]

transcription coactivator binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

protein-folding chaperone binding

ion binding [inference]

cation binding [inference]

metal ion binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

sequence-specific DNA binding [inference]

telomeric DNA binding

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

telomerase

Functional Category

J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 9** entries
Gene Ontology
RNA-directed DNA polymerase activity
RNA-templated DNA biosynthetic process
metal ion binding
nucleotidyltransferase activity
telomerase RNA binding
telomerase RNA reverse transcriptase activity
telomere maintenance via telomerase
telomeric DNA binding
transferase activity

Disease

Disease Ontology

Displaying entries **1 - 10** of 17 in total

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DO ID	Disease Name	Source
DOID:0050156	idiopathic pulmonary fibrosis	Alliance of Genome Resources
DOID:0050685	small cell carcinoma	Alliance of Genome Resources
DOID:0050866	oral squamous cell carcinoma	Alliance of Genome Resources
DOID:0070016	autosomal dominant dyskeratosis congenita 2	Alliance of Genome Resources
DOID:11054	urinary bladder cancer	Alliance of Genome Resources
DOID:1319	brain cancer	Alliance of Genome Resources
DOID:1909	melanoma	Alliance of Genome Resources
DOID:3748	esophagus squamous cell carcinoma	Alliance of Genome Resources
DOID:3907	lung squamous cell carcinoma	Alliance of Genome Resources
DOID:3908	lung non-small cell carcinoma	Alliance of Genome Resources

Ortholog

Displaying entries **41 - 50** of 63 in total

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Species	Gene ID	Orthologous MAtrix
Salmo salar	106570713	SALSA33113
Equus asinus asinus	106835880	EQUAS19521
Ictalurus punctatus	108274792	ICTPU05791
Rhinopithecus bieti	108513704	RHIBE36846
Cyprinus carpio carpio	109111099	CYPCA77718
Phascolarctos cinereus	110201216	PHACI19815
Oryzias melastigma	112136283	ORYME32263
Pseudonaja textilis	113436445	PSETE07669
Electrophorus electricus	113590696	ELEEL45506
Bos indicus x Bos taurus	113879082	BOBOX35653

GlyTouCan

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Acknowledgements