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rhodopsin

Summary

Gene Symbol

RHO

Organism

Macaca mulatta (Rhesus monkey)

External Links

NCBI Gene: 702931
PubChem: 702931

Annotation

Keyword

Cell projection
Disulfide bond
G-protein coupled receptor
Glycoprotein
Lipoprotein
Metal-binding
Phosphoprotein
Reference proteome
Retinal protein
Transmembrane helix
Vision
Zinc

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A8J8YFX4
F7ETG0

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
microtubule cytoskeleton organization
thermotaxis
response to light intensity
cellular response to light stimulus
rod bipolar cell differentiation

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

gene expression

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization

signal transduction [inference]

light absorption [inference]

absorption of visible light

cellular metabolic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

gene expression

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

glutamatergic neuron differentiation [inference]

retinal bipolar neuron differentiation [inference]

rod bipolar cell differentiation

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

podosome assembly

cellular component assembly [inference]

protein-containing complex assembly [inference]

podosome assembly

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

podosome assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

podosome assembly

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

photoreceptor cell maintenance

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

glutamatergic neuron differentiation [inference]

retinal bipolar neuron differentiation [inference]

rod bipolar cell differentiation

locomotion [inference]

taxis [inference]

thermotaxis

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

response to abiotic stimulus [inference]

response to temperature stimulus [inference]

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

thermotaxis

response to radiation [inference]

response to light stimulus [inference]

detection of light stimulus [inference]

phototransduction

cellular response to radiation [inference]

cellular response to light stimulus

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

detection of stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

phototransduction

detection of temperature stimulus [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

detection of stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in sensory perception [inference]

detection of temperature stimulus involved in thermoception

cellular response to stimulus [inference]

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to light stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
photoreceptor outer segment membrane
sperm midpiece
membrane	IEA	22301074
Golgi apparatus
plasma membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

photoreceptor outer segment

rod photoreceptor outer segment

plasma membrane

organelle membrane [inference]

photoreceptor disc membrane

bounding membrane of organelle [inference]

ciliary membrane [inference]

photoreceptor outer segment membrane

plasma membrane region [inference]

cell projection membrane [inference]

ciliary membrane [inference]

photoreceptor outer segment membrane

cell junction [inference]

anchoring junction [inference]

cell-cell junction

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

sperm midpiece

Displaying **all 4** entries
GO Term	Evidence Code	PMID
metal ion binding
G protein-coupled photoreceptor activity
photoreceptor activity
G protein-coupled receptor activity	IEA	22301074

GO Hierarchy

molecular function

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

molecular transducer activity [inference]

signaling receptor activity [inference]

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity

G protein-coupled photoreceptor activity

photoreceptor activity

G protein-coupled photoreceptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

green-sensitive opsin

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
cellular response to light stimulus
metal ion binding
photoreceptor activity
phototransduction
visual perception

Displaying **all 6** entries
InterPro
G protein-coupled receptor, rhodopsin-like
GPCR, rhodopsin-like, 7TM
Opsin
Rhodopsin, N-terminal
Rhodopsin
Visual pigments (opsins) retinal binding site

Ortholog

Displaying entries **1 - 10** of 79 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6010			HUMAN72230
Rattus norvegicus	24717			RATNO29856
Mus musculus	212541			MOUSE50392
Sus scrofa	397437			PIGXX04624
Pan troglodytes	460685			PANTR32158
Felis catus	493762			FELCA05036
Canis lupus familiaris	493763			CANLF07257
Bos taurus	509933			BOVIN18052
Taeniopygia guttata	751971			TAEGU03490
Oryctolagus cuniculus	100009200			RABIT12719

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Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 9, 2024