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thrombospondin 1
Summary
- Gene Symbol
-
- THBS1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Angiogenesis
- Apoptosis
- Calcium
- Cell adhesion
- Disulfide bond
- EGF-like domain
- Endoplasmic reticulum
- Extracellular matrix
- Glycoprotein
- Heparin-binding
- Inflammatory response
- Proteomics identification
- Reference proteome
- Repeat
- Sarcoplasmic reticulum
- Signal
- Unfolded protein response
- Proteins
| UniProt | Protein Name |
|---|---|
| P07996 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| response to magnesium ion | ||
| response to progesterone | ||
| negative regulation of interleukin-10 production | ||
| negative regulation of interleukin-12 production | ||
| negative regulation of tumor necrosis factor production |
GO Hierarchy
- negative regulation of fibrinolysis
biological process
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
negative regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
negative regulation of macromolecule metabolic process [inference]
regulation of protein metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of signaling [inference]
positive regulation of locomotion [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
negative regulation of metabolic process [inference]
negative regulation of cellular process [inference]
negative regulation of response to stimulus [inference]
regulation of response to stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
negative regulation of response to stimulus [inference]
regulation of cellular response to growth factor stimulus [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
negative regulation of cellular metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of phosphorus metabolic process [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| collagen-containing extracellular matrix | ||
| collagen-containing extracellular matrix | ||
| collagen-containing extracellular matrix | ||
| extracellular exosome |
| GO Term | Evidence Code | PMID |
|---|---|---|
| phosphatidylserine binding | ||
| fibronectin binding | ||
| protease binding | ||
| endopeptidase inhibitor activity | ||
| integrin binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- thrombospondin-1
- Functional Category
-
- I: Lipid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| calcium ion binding |
| heparin binding |
| negative regulation of angiogenesis |
