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TIA1 cytotoxic granule associated RNA binding protein like 1

Summary

Gene Symbol

TIAL1

Organism

Homo sapiens (human)

External Links

NCBI Gene

7073

PubChem

7073

Alliance of Genome Resources

HGNC:11804

JoGo

TIAL1

TogoVar

TIAL1

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Apoptosis
Cytoplasm
Lysosome
Nucleus
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome
Repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q01085	TIA-1-related protein
Q49AS9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
regulation of transcription by RNA polymerase II	TAS	9207209
apoptotic process	IEA
defense response	TAS	1326761
germ cell development	IEA
negative regulation of cell population proliferation	IMP	33203680

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

cell population proliferation [inference]

stem cell proliferation

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

cellular developmental process [inference]

cell development [inference]

germ cell development

cell division [inference]

stem cell division

reproductive process [inference]

developmental process involved in reproduction [inference]

germ cell development

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development

anatomical structure development [inference]

cell development [inference]

germ cell development

cellular developmental process [inference]

cell development [inference]

germ cell development

response to stimulus [inference]

response to stress [inference]

defense response

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of gene silencing by regulatory ncRNA [inference]

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of gene silencing by regulatory ncRNA [inference]

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of gene silencing by regulatory ncRNA [inference]

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

regulation of intracellular signal transduction [inference]

regulation of hippo signaling [inference]

positive regulation of hippo signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of stem cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

regulation of intracellular signal transduction [inference]

regulation of hippo signaling [inference]

positive regulation of hippo signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

regulation of intracellular signal transduction [inference]

regulation of hippo signaling [inference]

positive regulation of hippo signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of gene silencing by regulatory ncRNA [inference]

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of stem cell proliferation

negative regulation of cell population proliferation

regulation of stem cell proliferation [inference]

positive regulation of stem cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of stem cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nucleus	ISS
nucleoplasm	TAS
nucleoplasm	IDA
cytoplasm	ISS
lysosome	TAS	1326761

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

cytolytic granule

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

cytolytic granule

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
DNA binding	IEA
RNA binding	HDA	22658674 22681889
mRNA 3'-UTR binding	IDA	33203680
protein binding	IPI	28514442 32296183 33961781 34517762
mRNA 3'-UTR AU-rich region binding	IEA