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TIA1 cytotoxic granule associated RNA binding protein like 1

Summary

Gene Symbol

TIAL1

Organism

Homo sapiens (human)

External Links

NCBI Gene

7073

PubChem

7073

Alliance of Genome Resources

HGNC:11804

JoGo

TIAL1

TogoVar

TIAL1

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Apoptosis
Cytoplasm
Lysosome
Nucleus
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome
Repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q01085	TIA-1-related protein
Q49AS9

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
stem cell division	IEA
positive regulation of hippo signaling	IMP	33203680
stem cell proliferation	IEA
positive regulation of miRNA-mediated gene silencing	IGI	33203680
positive regulation of stem cell proliferation	IEA

GO Hierarchy

biological process

cellular process [inference]

cell death [inference]

programmed cell death [inference]

apoptotic process

cell population proliferation [inference]

stem cell proliferation

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

cellular developmental process [inference]

cell development [inference]

germ cell development

cell division [inference]

stem cell division

reproductive process [inference]

developmental process involved in reproduction [inference]

germ cell development

cellular process involved in reproduction in multicellular organism [inference]

germ cell development

developmental process [inference]

developmental process involved in reproduction [inference]

germ cell development

anatomical structure development [inference]

cell development [inference]

germ cell development

cellular developmental process [inference]

cell development [inference]

germ cell development

response to stimulus [inference]

response to stress [inference]

defense response

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of gene silencing by regulatory ncRNA [inference]

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of gene silencing by regulatory ncRNA [inference]

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of gene silencing by regulatory ncRNA [inference]

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

regulation of intracellular signal transduction [inference]

regulation of hippo signaling [inference]

positive regulation of hippo signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of stem cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

regulation of intracellular signal transduction [inference]

regulation of hippo signaling [inference]

positive regulation of hippo signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

regulation of intracellular signal transduction [inference]

regulation of hippo signaling [inference]

positive regulation of hippo signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

regulation of RNA metabolic process [inference]

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing [inference]

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of gene silencing by regulatory ncRNA [inference]

regulation of post-transcriptional gene silencing by regulatory ncRNA [inference]

regulation of miRNA-mediated gene silencing [inference]

positive regulation of miRNA-mediated gene silencing

positive regulation of post-transcriptional gene silencing by RNA [inference]

positive regulation of miRNA-mediated gene silencing

regulation of RNA biosynthetic process [inference]

regulation of DNA-templated transcription [inference]

regulation of transcription by RNA polymerase II

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation [inference]

positive regulation of stem cell proliferation

negative regulation of cell population proliferation

regulation of stem cell proliferation [inference]

positive regulation of stem cell proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation [inference]

positive regulation of stem cell proliferation

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of hippo signaling

negative regulation of cellular process [inference]

negative regulation of cell population proliferation

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
nucleus	ISS
nucleoplasm	TAS
nucleoplasm	IDA
cytoplasm	ISS
lysosome	TAS	1326761

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

cytolytic granule

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

vacuole [inference]

lytic vacuole [inference]

lysosome

cytolytic granule

intracellular non-membrane-bounded organelle [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule [inference]

cytoplasmic stress granule

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
DNA binding	IEA
RNA binding	HDA	22658674 22681889
mRNA 3'-UTR binding	IDA	33203680
protein binding	IPI	28514442 32296183 33961781 34517762
mRNA 3'-UTR AU-rich region binding	IEA