GlyCosmos Portal

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GO Term	Evidence Code	PMID
peptidylglycine monooxygenase activity	IEA	30032202
peptidylamidoglycolate lyase activity
copper ion binding	IEA	22301074
protein binding	IEA	22301074
zinc ion binding

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity [inference]

monooxygenase activity [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [inference]

peptidylglycine monooxygenase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen [inference]

peptidylglycine monooxygenase activity

lyase activity [inference]

carbon-nitrogen lyase activity [inference]

amidine-lyase activity [inference]

peptidylamidoglycolate lyase activity

catalytic activity, acting on a protein [inference]

peptidylamidoglycolate lyase activity

binding [inference]

protein binding

carbohydrate binding [inference]

monosaccharide binding [inference]

L-ascorbic acid binding

small molecule binding [inference]

vitamin binding [inference]

L-ascorbic acid binding

organic acid binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

monosaccharide binding [inference]

L-ascorbic acid binding

heterocyclic compound binding [inference]

L-ascorbic acid binding

ion binding [inference]

anion binding [inference]

carboxylic acid binding [inference]

L-ascorbic acid binding

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

organic cyclic compound binding [inference]

L-ascorbic acid binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Peptidyl-glycine alpha-amidating monooxygenase

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 7** entries
Gene Ontology
catalytic activity
copper ion binding
metal ion binding
monooxygenase activity
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
peptide metabolic process
peptidylglycine monooxygenase activity

Displaying **all 8** entries
InterPro
Copper type II ascorbate-dependent monooxygenase, C-terminal
Copper type II, ascorbate-dependent monooxygenase, N-terminal domain superfamily
Copper type II, ascorbate-dependent monooxygenase, N-terminal
Copper type II, ascorbate-dependent monooxygenase-like, C-terminal
NHL repeat
PHM/PNGase F domain superfamily
Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyase
Six-bladed beta-propeller, TolB-like

Ortholog

Displaying entries **1 - 10** of 81 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	5066	HUMAN80199
Mus musculus	18484	MOUSE30132
Rattus norvegicus	25508	RATNO43121
Bos taurus	280890	BOVIN34034
Pan troglodytes	461974	PANTR35852
Danio rerio	570822	DANRE00295
Monodelphis domestica	100030601	MONDO16536
Ornithorhynchus anatinus	100073355	ORNAN01447
Oryctolagus cuniculus	100352005	RABIT01820
Callithrix jacchus	100396001	CALJA25194