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intercellular adhesion molecule 5

Summary

Gene Symbol

ICAM5

Aliases

TLN
telencephalin

Organism

Homo sapiens (human)

External Links

NCBI Gene

7087

HGNC

5348

KEGG Gene ID

hsa:7087

PubChem

7087

Alliance of Genome Resources

HGNC:5348

Annotation

Keyword

3D-structure
Cell adhesion
Disulfide bond
Glycoprotein
Immunoglobulin domain
Phosphoprotein
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9UMF0	Telencephalin
Q8N6I2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
regulation of synapse assembly	IEA
cell-cell adhesion	IEA
phagocytosis	IEA
cell adhesion	IBA

GO Hierarchy

biological process

cellular process [inference]

cell-cell adhesion

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

localization [inference]

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endocytosis [inference]

phagocytosis

import into cell [inference]

endocytosis [inference]

phagocytosis

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glutamatergic synapse	IEA
plasma membrane	IBA TAS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction [inference]

synapse [inference]

glutamatergic synapse

Displaying **all 2** entries
GO Term	Evidence Code	PMID
integrin binding	IBA
protein binding	IPI	16820411 32814053

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

integrin binding

cell adhesion molecule binding [inference]

integrin binding

protein-containing complex binding [inference]

integrin binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000105376

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K06769

Name

intercellular adhesion molecule 5

References

7794412

Disease

Disease Ontology

Displaying entries **11 - 20** of 25 in total

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DO ID	Disease Name	Source
DOID:2377	multiple sclerosis	DisGeNET
DOID:2723	dermatitis	DisGeNET
DOID:322	myelitis	DisGeNET
DOID:4398	pustulosis of palm and sole	DisGeNET
DOID:4766	embryoma	DisGeNET
DOID:4866	salivary gland adenoid cystic carcinoma	DisGeNET
DOID:5672	large intestine cancer	DisGeNET DisGeNET
DOID:640	encephalomyelitis	DisGeNET
DOID:74	hematopoietic system disease	DisGeNET
DOID:8544	chronic fatigue syndrome	DisGeNET

Ortholog

Displaying entries **1 - 10** of 48 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	100002730	ZFIN:ZDB-GENE-040108-6
Xenopus laevis	494840	Xenbase:XB-GENE-6255071
Xenopus laevis	108713335	Xenbase:XB-GENE-17338817
Callithrix jacchus	100401727		CALJA22779
Cercocebus atys	105601440		CERAT21629
Macaca mulatta	720495		MACMU20198
Macaca nemestrina	105476665		MACNE12249
Papio anubis	101021361		PAPAN23333
Mandrillus leucophaeus	105550110		MANLE22632
Gorilla gorilla gorilla	109024166		GORGO15964

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024