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toll like receptor 2
Summary
- Gene Symbol
-
- TLR2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Cytoplasmic vesicle
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Innate immunity
- Isopeptide bond
- Leucine-rich repeat
- NAD
- Receptor
- Reference proteome
- Repeat
- Signal
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| O60603 |
|
| A0A0S2Z4S4 |
|
| B3KWR9 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| cellular response to triacyl bacterial lipopeptide | ||
| positive regulation of nitric-oxide synthase biosynthetic process | ||
| negative regulation of cell population proliferation | ||
| positive regulation of NF-kappaB transcription factor activity | ||
| nitric oxide metabolic process |
GO Hierarchy
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of cellular response to macrophage colony-stimulating factor stimulus
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of nitric-oxide synthase biosynthetic process
- positive regulation of cellular response to macrophage colony-stimulating factor stimulus
biological process
immune system process [inference]
metabolic process [inference]
cellular process [inference]
response to stimulus [inference]
response to external stimulus [inference]
response to biotic stimulus [inference]
response to chemical [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of primary metabolic process [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to cytokine stimulus [inference]
regulation of response to stress [inference]
regulation of developmental process [inference]
regulation of cellular process [inference]
signal transduction
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of cell differentiation [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of gene expression
positive regulation of cytokine production [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of cytokine production [inference]
positive regulation of multicellular organismal process [inference]
positive regulation of cytokine production [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| cell projection | ||
| phagocytic vesicle membrane | ||
| Golgi apparatus | ||
| membrane raft |
| GO Term | Evidence Code | PMID |
|---|---|---|
| transmembrane signaling receptor activity | ||
| NAD+ nucleotidase, cyclic ADP-ribose generating | ||
| amyloid-beta binding | ||
| lipopolysaccharide binding | ||
| Toll-like receptor binding |
GO Hierarchy
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0080998 | acute necrotizing pancreatitis | |
| DOID:0050127 | sinusitis | |
| DOID:0050855 | renal fibrosis | |
| DOID:0060189 | ileitis | |
| DOID:0060224 | atrial fibrillation | |
| DOID:0060322 | mastoiditis | |
| DOID:0080176 | meningococcal meningitis | |
| DOID:0080784 | urinary tract infection | |
| DOID:10140 | dry eye syndrome | |
| DOID:10223 | dermatomyositis |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 574290 | MACMU37102 | ||
| 105463507 | MACNE07368 | ||
| 103884712 | PAPAN27558 | ||
| 105531455 | MANLE35492 | ||
| 101128447 | GORGO30481 | ||
| 100994768 | PANPA31156 | ||
| 471325 | PANTR34663 | ||
| 100456464 | PONAB28066 | ||
| 448807 | CANLF04342 | ||
| 112933419 | VULVU29345 |
