tumor protein p53

Summary
Gene Symbol
  • TP53
Organism
Homo sapiens (human)
External Links
NCBI Gene
7157
PubChem
7157
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Acetylation
  • Activator
  • Alternative promoter usage
  • Alternative splicing
  • Apoptosis
  • Biological rhythms
  • Cell cycle
  • Cytoplasm
  • Cytoskeleton
  • DNA-binding
  • Direct protein sequencing
  • Disease variant
  • Endoplasmic reticulum
  • Glycoprotein
  • Host-virus interaction
  • Isopeptide bond
  • Li-Fraumeni syndrome
  • Metal-binding
  • Methylation
  • Mitochondrion
  • Necrosis
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • Reference proteome
  • Repressor
  • Transcription regulation
  • Tumor suppressor
  • Ubl conjugation
  • Zinc
Proteins
Displaying all 7 entries
UniProt Protein Name
A0A087WT22
H2EHT1
A0A087WXZ1
P04637
  • Antigen NY-CO-13
  • Phosphoprotein p53
  • Tumor suppressor p53
K7PPA8
A0A087X1Q1
Q53GA5
  • Tumor suppressor p53
Gene Ontology (GO)
Displaying entries 126 - 128 of 128 in total
GO Term Evidence Code PMID
response to ischemia
DNA damage response
neuroblast proliferation
GO Hierarchy
Displaying entries 26 - 30 of 35 in total
GO Term Evidence Code PMID
molecular function activator activity
protein binding
transcription cis-regulatory region binding
RNA polymerase II cis-regulatory region sequence-specific DNA binding
protease binding
GO Hierarchy
Disease
Disease Ontology
Displaying entries 11 - 20 of 79 in total
DO ID Disease Name Source
DOID:0060074 ductal carcinoma in situ
DOID:0080199 colorectal carcinoma
DOID:0080202 adenoid cystic carcinoma
DOID:0080630 B-lymphoblastic leukemia/lymphoma
DOID:0081267 graft-versus-host disease
DOID:0081292 traumatic brain injury
DOID:0081312 T-cell non-Hodgkin lymphoma
DOID:0111503 Li-Fraumeni syndrome 1
DOID:0112182 mismatch repair cancer syndrome
DOID:10283 prostate cancer

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: August 19, 2024