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complement C2

Summary

Gene Symbol

Organism

Homo sapiens (human)

External Links

NCBI Gene

717

PubChem

717

Alliance of Genome Resources

HGNC:1248

JoGo

TogoVar

Gene Ontology (GO)

Displaying entries **6 - 10** of 10 in total

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GO Term	Evidence Code	PMID
response to bacterium	IBA
response to lipopolysaccharide	IEA
innate immune response	IEA
response to thyroid hormone	IEA
positive regulation of apoptotic cell clearance	IMP	19302245

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

complement activation

complement activation, classical pathway

activation of immune response [inference]

complement activation

complement activation, classical pathway

immune response [inference]

humoral immune response [inference]

complement activation

complement activation, classical pathway

innate immune response

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

defense response to other organism [inference]

innate immune response

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

innate immune response

immune response [inference]

humoral immune response [inference]

complement activation

complement activation, classical pathway

innate immune response

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

response to nutrient

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to bacterium

defense response to other organism [inference]

innate immune response

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to other organism [inference]

response to bacterium

defense response to other organism [inference]

innate immune response

response to endogenous stimulus [inference]

response to hormone [inference]

response to thyroid hormone

response to chemical [inference]

response to nutrient

response to organic substance [inference]

response to molecule of bacterial origin [inference]

response to lipopolysaccharide

response to hormone [inference]

response to thyroid hormone

response to lipid [inference]

response to lipopolysaccharide

response to oxygen-containing compound [inference]

response to lipopolysaccharide

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

complement activation, classical pathway

regulation of immune response [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

complement activation, classical pathway

regulation of localization [inference]

regulation of transport [inference]

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of apoptotic cell clearance

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of apoptotic cell clearance

regulation of phagocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of apoptotic cell clearance

regulation of apoptotic cell clearance [inference]

positive regulation of apoptotic cell clearance

positive regulation of biological process [inference]

positive regulation of immune system process [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

complement activation, classical pathway

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of apoptotic cell clearance

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

complement activation, classical pathway

positive regulation of transport [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of apoptotic cell clearance

regulation of response to stimulus [inference]

positive regulation of response to stimulus [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

complement activation, classical pathway

regulation of immune response [inference]

positive regulation of immune response [inference]

activation of immune response [inference]

complement activation

complement activation, classical pathway

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of apoptotic cell clearance

regulation of cellular component organization [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of apoptotic cell clearance

regulation of phagocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of apoptotic cell clearance

regulation of apoptotic cell clearance [inference]

positive regulation of apoptotic cell clearance

positive regulation of cellular component organization [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of apoptotic cell clearance

regulation of vesicle-mediated transport [inference]

regulation of endocytosis [inference]

positive regulation of endocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of apoptotic cell clearance

regulation of phagocytosis [inference]

positive regulation of phagocytosis [inference]

positive regulation of apoptotic cell clearance

regulation of apoptotic cell clearance [inference]

positive regulation of apoptotic cell clearance

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular region	TAS
extracellular space	TAS	8621452
extracellular exosome	HDA	23533145

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
serine-type endopeptidase activity	IEA
protein binding	IPI	25910212 28742139 32296183
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

serine hydrolase activity [inference]

serine-type peptidase activity [inference]

serine-type endopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

serine-type endopeptidase activity

serine-type peptidase activity [inference]

serine-type endopeptidase activity

binding [inference]

protein binding

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying **all 5** entries
DO ID	Disease Name	Source
DOID:0060295	complement component 2 deficiency	Alliance of Genome Resources
DOID:0110026	age related macular degeneration 14	Alliance of Genome Resources
DOID:10652	Alzheimer's disease	Alliance of Genome Resources
DOID:4448	macular degeneration	Alliance of Genome Resources
DOID:8893	psoriasis	Alliance of Genome Resources