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kinesin family member 23

Summary

Gene Symbol

Kif23

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

71819

PubChem

71819

Alliance of Genome Resources

MGI:1919069

Annotation

Keyword

ATP-binding
Coiled coil
Cytoskeleton
Isopeptide bond
Microtubule
Mitosis
Motor protein
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
E9Q5G3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
mitotic cytokinesis	ISO ISS
mitotic spindle midzone assembly	IBA ISO
microtubule-based movement	IBA IEA
positive regulation of cytokinesis	ISO

GO Hierarchy

biological process

cellular process [inference]

microtubule-based process [inference]

microtubule-based movement

spindle midzone assembly [inference]

mitotic spindle midzone assembly

cell cycle process [inference]

cytokinesis [inference]

cytoskeleton-dependent cytokinesis [inference]

mitotic cytokinesis

spindle midzone assembly [inference]

mitotic spindle midzone assembly

mitotic cell cycle process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

spindle midzone assembly [inference]

mitotic spindle midzone assembly

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cellular process [inference]

positive regulation of cellular process [inference]

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cell division [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis

positive regulation of cell division [inference]

positive regulation of cytokinesis

regulation of cell cycle [inference]

regulation of cell cycle process [inference]

regulation of cytokinesis [inference]

positive regulation of cytokinesis

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

positive regulation of cell cycle [inference]

positive regulation of cell cycle process [inference]

positive regulation of cytokinesis

Displaying entries **11 - 12** of 12 in total

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GO Term	Evidence Code	PMID
cytoplasm	IBA IEA
mitotic spindle	IEA ISO

GO Hierarchy

cellular component

protein-containing complex [inference]

microtubule associated complex [inference]

kinesin complex

intracellular protein-containing complex [inference]

centralspindlin complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

midbody

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

mitotic spindle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

mitotic spindle

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule

Displaying **all 4** entries
GO Term	Evidence Code	PMID
ATP hydrolysis activity	IBA
microtubule binding	IBA IEA ISO
ATP binding	IEA
microtubule motor activity	IBA IEA

GO Hierarchy

molecular function

cytoskeletal motor activity [inference]

microtubule motor activity

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

tubulin binding [inference]

microtubule binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

microtubule motor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Kinesin-like protein

Functional Category

G: Carbohydrate transport and metabolism
J: Translation, ribosomal structure and biogenesis
K: Transcription
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 6** entries
Gene Ontology
ATP binding
cytoskeletal motor activity
microtubule binding
microtubule-based movement
mitotic spindle midzone assembly
nucleotide binding

Displaying **all 7** entries
InterPro
Kinesin motor domain superfamily
Kinesin motor domain, conserved site
Kinesin motor domain
Kinesin-like protein Kif23, Arf6-interacting domain superfamily
Kinesin-like protein Kif23, Arf6-interacting domain
Kinesin-like protein
P-loop containing nucleoside triphosphate hydrolase

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0111399	congenital dyserythropoietic anemia type III	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of **111** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	9493		HGNC:6392	HUMAN23873
Danio rerio	30627		ZFIN:ZDB-GENE-991019-4	DANRE14086
Drosophila melanogaster	38515		FB:FBgn0011692
Caenorhabditis elegans	177374		WB:WBGene00006974
Rattus norvegicus	315740	10116_1:002f24	RGD:1308596	RATNO42224
Pan troglodytes	453544			PANTR10677
Canis lupus familiaris	478355			CANLF12650
Xenopus tropicalis	496517		Xenbase:XB-GENE-999865
Bos taurus	515748			BOVIN00539
Macaca mulatta	695229			MACMU42193

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Last updated: December 9, 2024