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Guidelines

MIRAGE

uridine monophosphate synthetase

Summary

Gene Symbol

UMPS

Aliases

orotate phosphoribosyl transferase and orotidine-5'-decarboxylase

Organism

Homo sapiens (human)

External Links

NCBI Gene

7372

HGNC

12563

KEGG Gene ID

PubChem

7372

Alliance of Genome Resources

HGNC:12563

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Decarboxylase
Disease variant
Glycosyltransferase
Multifunctional enzyme
Phosphoprotein
Proteomics identification
Pyrimidine biosynthesis
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P11172
A8K5J1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 8** of 8 in total

« First

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1

2
GO Term	Evidence Code	PMID
UDP biosynthetic process	IEA
pyrimidine nucleobase biosynthetic process	IBA
'de novo' UMP biosynthetic process	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

phosphorus metabolic process [inference]

organophosphate metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

pyrimidine nucleotide metabolic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

pyrimidine ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

UMP metabolic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

nucleotide biosynthetic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

UMP metabolic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

nucleoside monophosphate metabolic process [inference]

nucleoside monophosphate biosynthetic process [inference]

pyrimidine nucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

pyrimidine nucleoside monophosphate metabolic process [inference]

pyrimidine nucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

pyrimidine ribonucleoside monophosphate metabolic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UMP metabolic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate biosynthetic process [inference]

pyrimidine nucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

ribonucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

pyrimidine nucleoside diphosphate metabolic process [inference]

pyrimidine nucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

pyrimidine ribonucleoside diphosphate metabolic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

ribonucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

pyrimidine ribonucleoside diphosphate metabolic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleoside monophosphate biosynthetic process [inference]

pyrimidine nucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

nucleoside diphosphate biosynthetic process [inference]

pyrimidine nucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

ribonucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

nucleotide biosynthetic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

UMP metabolic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

organophosphate biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleoside monophosphate biosynthetic process [inference]

pyrimidine nucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

nucleoside diphosphate biosynthetic process [inference]

pyrimidine nucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

ribonucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

nucleotide biosynthetic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

biosynthetic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

nucleoside monophosphate biosynthetic process [inference]

pyrimidine nucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

nucleoside diphosphate biosynthetic process [inference]

pyrimidine nucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

ribonucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

nucleotide biosynthetic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

pyrimidine nucleobase biosynthetic process

'de novo' pyrimidine nucleobase biosynthetic process

organophosphate biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleoside monophosphate biosynthetic process [inference]

pyrimidine nucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

nucleoside diphosphate biosynthetic process [inference]

pyrimidine nucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

ribonucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

nucleotide biosynthetic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

carbohydrate derivative biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleobase-containing compound biosynthetic process [inference]

nucleoside phosphate biosynthetic process [inference]

nucleoside monophosphate biosynthetic process [inference]

pyrimidine nucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

nucleoside diphosphate biosynthetic process [inference]

pyrimidine nucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

ribonucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

nucleotide biosynthetic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

pyrimidine nucleotide metabolic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

pyrimidine ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

UMP metabolic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

nucleotide biosynthetic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

UMP metabolic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

nucleoside monophosphate metabolic process [inference]

nucleoside monophosphate biosynthetic process [inference]

pyrimidine nucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

pyrimidine nucleoside monophosphate metabolic process [inference]

pyrimidine nucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

pyrimidine ribonucleoside monophosphate metabolic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UMP metabolic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate biosynthetic process [inference]

pyrimidine nucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

ribonucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

pyrimidine nucleoside diphosphate metabolic process [inference]

pyrimidine nucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

pyrimidine ribonucleoside diphosphate metabolic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

ribonucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

pyrimidine ribonucleoside diphosphate metabolic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleoside monophosphate biosynthetic process [inference]

pyrimidine nucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

nucleoside diphosphate biosynthetic process [inference]

pyrimidine nucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

ribonucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

nucleotide biosynthetic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process

'de novo' pyrimidine nucleobase biosynthetic process

small molecule metabolic process [inference]

nucleobase-containing small molecule metabolic process [inference]

nucleoside phosphate metabolic process [inference]

nucleotide metabolic process [inference]

pyrimidine nucleotide metabolic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

pyrimidine ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

UMP metabolic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

nucleotide biosynthetic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

UMP metabolic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

nucleoside monophosphate metabolic process [inference]

nucleoside monophosphate biosynthetic process [inference]

pyrimidine nucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

pyrimidine nucleoside monophosphate metabolic process [inference]

pyrimidine nucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

pyrimidine ribonucleoside monophosphate metabolic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UMP metabolic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

nucleoside diphosphate metabolic process [inference]

nucleoside diphosphate biosynthetic process [inference]

pyrimidine nucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

ribonucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

pyrimidine nucleoside diphosphate metabolic process [inference]

pyrimidine nucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

pyrimidine ribonucleoside diphosphate metabolic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

ribonucleoside diphosphate metabolic process [inference]

ribonucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

pyrimidine ribonucleoside diphosphate metabolic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

nucleoside phosphate biosynthetic process [inference]

nucleoside monophosphate biosynthetic process [inference]

pyrimidine nucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleoside monophosphate biosynthetic process [inference]

pyrimidine ribonucleoside monophosphate biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

nucleoside diphosphate biosynthetic process [inference]

pyrimidine nucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

ribonucleoside diphosphate biosynthetic process [inference]

pyrimidine ribonucleoside diphosphate biosynthetic process [inference]

UDP biosynthetic process

nucleotide biosynthetic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

nucleobase metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process

'de novo' pyrimidine nucleobase biosynthetic process

nucleobase biosynthetic process [inference]

pyrimidine nucleobase biosynthetic process

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine-containing compound metabolic process [inference]

pyrimidine nucleobase metabolic process [inference]

pyrimidine nucleobase biosynthetic process

'de novo' pyrimidine nucleobase biosynthetic process

pyrimidine nucleotide metabolic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

pyrimidine ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

UMP metabolic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

pyrimidine-containing compound biosynthetic process [inference]

pyrimidine nucleotide biosynthetic process

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

pyrimidine nucleobase biosynthetic process

'de novo' pyrimidine nucleobase biosynthetic process

carbohydrate derivative metabolic process [inference]

ribose phosphate metabolic process [inference]

ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide metabolic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

UDP metabolic process [inference]

UDP biosynthetic process

UMP metabolic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

carbohydrate derivative biosynthetic process [inference]

ribose phosphate biosynthetic process [inference]

ribonucleotide biosynthetic process [inference]

pyrimidine ribonucleotide biosynthetic process [inference]

UMP biosynthetic process

'de novo' UMP biosynthetic process

UDP biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
nucleus	IDA
cytoplasm	IDA
cytosol	TAS

GO Hierarchy

cellular component

cellular anatomical structure [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 8 in total

1

2

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GO Term	Evidence Code	PMID
orotate phosphoribosyltransferase activity	IDA
orotate phosphoribosyltransferase activity	IBA
orotate phosphoribosyltransferase activity	IEA
orotidine-5'-phosphate decarboxylase activity	IDA
orotidine-5'-phosphate decarboxylase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

pentosyltransferase activity [inference]

orotate phosphoribosyltransferase activity

lyase activity [inference]

carbon-carbon lyase activity [inference]

carboxy-lyase activity [inference]

orotidine-5'-phosphate decarboxylase activity

binding [inference]

protein binding

identical protein binding

Gene Ontology information from NCBI Gene and UniProt.

Rhea

diphosphate + orotidine 5'-phosphate

orotate + 5-phospho-α-D-ribose 1-diphosphate

Enzyme

2.4.2.10

PMID

H⁺ + orotidine 5'-phosphate

CO₂ + UMP

Enzyme

4.1.1.23

PMID

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0050833	orotic aciduria	Alliance of Genome Resources
DOID:653	purine-pyrimidine metabolic disorder	Alliance of Genome Resources

The Human Phenotype Ontology

Displaying entries **1 - 10** of 26 in total

1

2

3

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HPO ID	HPO Term
HP:0000007	Autosomal recessive inheritance
HP:0000069	Abnormality of the ureter
HP:0000316	Hypertelorism
HP:0000368	Low-set, posteriorly rotated ears
HP:0000431	Wide nasal bridge
HP:0000494	Downslanted palpebral fissures
HP:0000790	Hematuria
HP:0001263	Global developmental delay
HP:0001385	Hip dysplasia
HP:0001508	Failure to thrive

Displaying **all 2** entries
Disease ID	Disease Name
ORPHA:30	orotic aciduria
OMIM:258900	orotic aciduria

PubChem Disease

MedGen Diseases

Oroticaciduria

OMIM Phenotypes

OROTIC ACIDURIA

KEGG Diseases

Orotic aciduria

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying **all 4** entries
Species	Gene ID	Alliance of Genome Resources
Mus musculus	22247	MGI:1298388
Caenorhabditis elegans	172008	WB:WBGene00020036
Caenorhabditis elegans	176453	WB:WBGene00011559
Drosophila melanogaster	42493	FB:FBgn0003257

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Last updated: April 6, 2026