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FIC domain protein adenylyltransferase

Summary

Gene Symbol

FICD

Organism

Pan troglodytes (chimpanzee)

External Links

NCBI Gene: 743566
PubChem: 743566

Annotation

Keyword

ATP-binding
Membrane
Nucleotidyltransferase
Reference proteome
TPR repeat

Proteins

Displaying **all 3** entries
UniProt	Protein Name
H2Q6T3	AMPylator FICD FIC domain-containing protein
A0A6D2XSB9	AMPylator FICD FIC domain-containing protein
G2HHH4	AMPylator FICD FIC domain-containing protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein adenylylation
response to endoplasmic reticulum stress
regulation of IRE1-mediated unfolded protein response

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein nucleotidylation [inference]

protein adenylylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein nucleotidylation [inference]

protein adenylylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein nucleotidylation [inference]

protein adenylylation

macromolecule modification [inference]

protein modification process [inference]

protein nucleotidylation [inference]

protein adenylylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein nucleotidylation [inference]

protein adenylylation

cellular process [inference]

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

cellular response to stimulus [inference]

cellular response to stress [inference]

response to endoplasmic reticulum stress

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

regulation of cellular response to stress [inference]

regulation of response to endoplasmic reticulum stress [inference]

regulation of endoplasmic reticulum unfolded protein response [inference]

regulation of IRE1-mediated unfolded protein response

Displaying **all 2** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum membrane
membrane

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein binding	IEA	22301074
ATP binding
Hsp70 protein binding
protein homodimerization activity
AMPylase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

nucleotidyltransferase activity [inference]

adenylyltransferase activity [inference]

AMPylase activity

binding [inference]

protein binding

heat shock protein binding [inference]

Hsp70 protein binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

protein-folding chaperone binding [inference]

Hsp70 protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

adenosine monophosphate-protein

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
AMPylase activity
ATP binding
nucleotide binding

Displaying **all 4** entries
InterPro
Fido domain-containing protein
Fido domain
Fido-like domain superfamily
Tetratricopeptide-like helical domain superfamily

Ortholog

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Homo sapiens	11153	HUMAN15194
Mus musculus	231630	MOUSE44982
Rattus norvegicus	288741	RATNO05970
Danio rerio	334648	DANRE36816
Bos taurus	505923	BOVIN09714
Macaca mulatta	706780	MACMU02940
Monodelphis domestica	100025324	MONDO18677
Equus caballus	100059882	HORSE41743
Ornithorhynchus anatinus	100076324	ORNAN14144
Taeniopygia guttata	100232426	TAEGU06117

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Acknowledgements