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MAM domain containing glycosylphosphatidylinositol anchor 1

Summary

Gene Symbol

Mdga1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

74762

PubChem

74762

Alliance of Genome Resources

MGI:1922012

Annotation

Keyword

Immunoglobulin domain
Proteomics identification
Reference proteome
Repeat
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
D3Z499

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
regulation of synaptic membrane adhesion	IEA ISO
presynapse assembly	IDA	23358245
neuron migration	IDA IMP	16641224 20473291
regulation of presynapse assembly	IEA ISO
nervous system development	IBA

GO Hierarchy

biological process

cellular process [inference]

cell motility [inference]

cell migration [inference]

neuron migration

forebrain cell migration [inference]

telencephalon cell migration [inference]

cerebral cortex cell migration [inference]

cerebral cortex radially oriented cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

cell junction assembly [inference]

synapse assembly [inference]

inhibitory synapse assembly

presynapse assembly

cell junction organization [inference]

cell junction assembly [inference]

synapse assembly [inference]

inhibitory synapse assembly

synapse organization [inference]

synapse assembly [inference]

inhibitory synapse assembly

presynapse organization [inference]

presynapse assembly

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

biological regulation [inference]

regulation of biological process [inference]

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly

negative regulation of developmental process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly

regulation of developmental process [inference]

negative regulation of developmental process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly

regulation of cellular process [inference]

regulation of cell adhesion [inference]

regulation of cell-cell adhesion [inference]

regulation of synaptic membrane adhesion

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly

negative regulation of cellular process [inference]

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly

regulation of cellular component organization [inference]

regulation of synapse organization [inference]

regulation of synapse assembly [inference]

regulation of presynapse organization [inference]

regulation of presynapse assembly

regulation of synaptic membrane adhesion

negative regulation of synapse organization [inference]

negative regulation of synapse assembly

negative regulation of cellular component organization [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly

negative regulation of synapse organization [inference]

negative regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly [inference]

negative regulation of cell junction assembly [inference]

negative regulation of synapse assembly

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly

regulation of multicellular organismal development [inference]

regulation of nervous system development [inference]

negative regulation of nervous system development [inference]

negative regulation of synapse assembly

regulation of molecular function [inference]

regulation of binding [inference]

regulation of protein binding

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
membrane
Golgi apparatus	IBA IEA ISO
plasma membrane	ISO ISS
membrane raft	ISO
side of membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane

plasma membrane

membrane microdomain [inference]

membrane raft

cell junction [inference]

synapse [inference]

GABA-ergic synapse

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

side of membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	23358245
molecular_function	ND

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

MAM domain-containing glycosylphosphatidylinositol anchor protein 1

Functional Category

F: Nucleotide transport and metabolism
T: Signal transduction mechanisms
X: Mobilome: prophages, transposons

Displaying **all 3** entries
Gene Ontology
axon guidance receptor activity
homophilic cell adhesion via plasma membrane adhesion molecules
synapse organization

Displaying **all 10** entries
InterPro
Concanavalin A-like lectin/glucanase domain superfamily
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin I-set
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
MAM domain

Ortholog

Displaying entries **1 - 10** of **112** in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	266727		HGNC:19267	HUMAN84620
Rattus norvegicus	309659	10116_1:0053ec	RGD:1307031	RATNO21618
Sus scrofa	397529			PIGXX31503
Pan troglodytes	471999			PANTR38073
Bos taurus	536481			BOVIN18416
Macaca mulatta	719423			MACMU35503
Ornithorhynchus anatinus	100076565			ORNAN10789
Taeniopygia guttata	100219729			TAEGU21657
Callithrix jacchus	100393141			CALJA32469
Pongo abelii	100432241			PONAB31494