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Wnt family member 2B

Summary

Gene Symbol

WNT2B

Organism

Homo sapiens (human)

External Links

NCBI Gene

7482

KEGG Gene ID

PubChem

7482

Alliance of Genome Resources

HGNC:12781

Annotation

Keyword

Alternative splicing
Developmental protein
Disease variant
Disulfide bond
Extracellular matrix
Glycoprotein
Lipoprotein
Proteomics identification
Reference proteome
Signal
Wnt signaling pathway

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q93097	Protein Wnt-13
Q5TEH8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 21 in total

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GO Term	Evidence Code	PMID
chondrocyte differentiation	IEP
lens development in camera-type eye	ISS
male gonad development	IEP
cellular response to starvation
Wnt signaling pathway	IEA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling [inference]

mesenchymal-epithelial cell signaling

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

canonical Wnt signaling pathway

cell population proliferation [inference]

stem cell proliferation [inference]

hematopoietic stem cell proliferation

cellular developmental process [inference]

cell differentiation [inference]

cell fate commitment

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

forebrain regionalization

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

anatomical structure morphogenesis [inference]

iris morphogenesis

developmental induction [inference]

organ induction [inference]

lung induction

anatomical structure development [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

system development

animal gross anatomical part developmental process [inference]

lens development in camera-type eye

animal organ development

gonad development [inference]

male gonad development

cornea development in camera-type eye

cellular developmental process [inference]

cell differentiation [inference]

cell fate commitment

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling [inference]

mesenchymal-epithelial cell signaling

positive regulation of biological process [inference]

positive regulation of developmental process [inference]

positive regulation of animal organ morphogenesis [inference]

organ induction [inference]

lung induction

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of branching involved in ureteric bud morphogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of branching involved in ureteric bud morphogenesis

positive regulation of animal organ morphogenesis [inference]

organ induction [inference]

lung induction

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of morphogenesis of a branching structure [inference]

regulation of branching involved in lung morphogenesis [inference]

lung induction

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of morphogenesis of an epithelium [inference]

regulation of branching involved in lung morphogenesis [inference]

lung induction

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of animal organ morphogenesis [inference]

regulation of animal organ formation [inference]

organ induction [inference]

lung induction

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

positive regulation of animal organ morphogenesis [inference]

organ induction [inference]

lung induction

positive regulation of developmental process [inference]

positive regulation of animal organ morphogenesis [inference]

organ induction [inference]

lung induction

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of kidney development [inference]

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of multicellular organismal development [inference]

regulation of embryonic development [inference]

lung induction

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

canonical Wnt signaling pathway

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of branching involved in ureteric bud morphogenesis

positive regulation of animal organ morphogenesis [inference]

organ induction [inference]

lung induction

regulation of morphogenesis of a branching structure [inference]

regulation of branching involved in lung morphogenesis [inference]

lung induction

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of multicellular organismal development [inference]

regulation of embryonic development [inference]

lung induction

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
extracellular region	EXP
extracellular region	NAS
extracellular region	TAS
extracellular region	IBA
extracellular region	IEA

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

external encapsulating structure [inference]

extracellular matrix

Displaying **all 4** entries
GO Term	Evidence Code	PMID
signaling receptor binding	IEA
frizzled binding	IBA
cytokine activity	IBA
protein binding	IPI

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding

G protein-coupled receptor binding [inference]

frizzled binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0060774	congenital diarrhea	Alliance of Genome Resources

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Xenopus laevis	378566	Xenbase:XB-GENE-960151
Mus musculus	22414	MGI:1261834
Caenorhabditis elegans	177870	WB:WBGene00000858

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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