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wingless-type MMTV integration site family, member 2B

Summary

Gene Symbol

Wnt2b

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

22414

KEGG Gene ID

PubChem

22414

Alliance of Genome Resources

MGI:1261834

Annotation

Keyword

Developmental protein
Disulfide bond
Extracellular matrix
Glycoprotein
Lipoprotein
Reference proteome
Signal
Wnt signaling pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
O70283	Protein Wnt-13

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
chondrocyte differentiation	IEA
signal transduction	TAS
cell-cell signaling	TAS
male gonad development	IEA
cellular response to starvation	IEP

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cell-cell signaling

mesenchymal-epithelial cell signaling

signal transduction

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

canonical Wnt signaling pathway

cell population proliferation [inference]

stem cell proliferation [inference]

hematopoietic stem cell proliferation

cellular developmental process [inference]

cell differentiation [inference]

cell fate commitment

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

multicellular organismal process [inference]

pattern specification process [inference]

regionalization [inference]

forebrain regionalization

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

anatomical structure morphogenesis [inference]

animal organ morphogenesis

developmental induction [inference]

organ induction [inference]

lung induction

anatomical structure development [inference]

reproductive structure development [inference]

gonad development [inference]

male gonad development

system development

animal gross anatomical part developmental process [inference]

animal organ development [inference]

gonad development [inference]

male gonad development

cellular developmental process [inference]

cell differentiation [inference]

cell fate commitment

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

response to nutrient levels [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

response to starvation [inference]

cellular response to starvation

cellular response to stimulus [inference]

cellular response to nutrient levels [inference]

cellular response to starvation

cellular response to stress [inference]

cellular response to starvation

biological regulation [inference]

regulation of biological process [inference]

signaling [inference]

cell-cell signaling

mesenchymal-epithelial cell signaling

positive regulation of biological process [inference]

positive regulation of developmental process [inference]

positive regulation of animal organ morphogenesis [inference]

organ induction [inference]

lung induction

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of branching involved in ureteric bud morphogenesis

positive regulation of multicellular organismal process [inference]

positive regulation of branching involved in ureteric bud morphogenesis

positive regulation of animal organ morphogenesis [inference]

organ induction [inference]

lung induction

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of morphogenesis of a branching structure [inference]

regulation of branching involved in lung morphogenesis [inference]

lung induction

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of morphogenesis of an epithelium [inference]

regulation of branching involved in lung morphogenesis [inference]

lung induction

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of animal organ morphogenesis [inference]

regulation of animal organ formation [inference]

organ induction [inference]

lung induction

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

positive regulation of animal organ morphogenesis [inference]

organ induction [inference]

lung induction

positive regulation of developmental process [inference]

positive regulation of animal organ morphogenesis [inference]

organ induction [inference]

lung induction

positive regulation of morphogenesis of an epithelium [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of kidney development [inference]

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of multicellular organismal development [inference]

regulation of embryonic development [inference]

lung induction

regulation of cellular process [inference]

signal transduction

cell surface receptor signaling pathway [inference]

Wnt signaling pathway

canonical Wnt signaling pathway

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of branching involved in ureteric bud morphogenesis

positive regulation of animal organ morphogenesis [inference]

organ induction [inference]

lung induction

regulation of morphogenesis of a branching structure [inference]

regulation of branching involved in lung morphogenesis [inference]

lung induction

regulation of branching involved in ureteric bud morphogenesis [inference]

positive regulation of branching involved in ureteric bud morphogenesis

regulation of multicellular organismal development [inference]

regulation of embryonic development [inference]

lung induction

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular region	IBA
extracellular region	IEA
obsolete extracellular space

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

Displaying **all 5** entries
GO Term	Evidence Code	PMID
signaling receptor binding	TAS
signaling receptor binding	IEA
frizzled binding	IBA
cytokine activity	IBA
protein binding	IPI

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding

G protein-coupled receptor binding [inference]

frizzled binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

Ortholog

Displaying **all 3** entries
Species	Gene ID	Alliance of Genome Resources
Homo sapiens	7482	HGNC:12781
Caenorhabditis elegans	177870	WB:WBGene00000858
Caenorhabditis elegans	173399	WB:WBGene00000857

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.5.0

Last updated: April 6, 2026

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