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MIRAGE
mannosidase endo-alpha

Summary
Gene Symbol
  • MANEA
Aliases
  • FLJ12838
  • endomannosidase
  • glycoprotein endo-alpha-1,2-mannosidase
  • mandaselin
Organism
Homo sapiens (human)
NCBI Gene
79694
HGNC
21072
KEGG Gene ID
hsa:79694
PubChem
79694
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • Golgi apparatus
  • Hydrolase
  • Reference proteome
  • Signal-anchor
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
Q5SRI9
  • Mandaselin
Annotation information from UniProt.
Gene Ontology (GO)
Gene Ontology information from NCBI Gene and UniProt.
OrthoDB (Group)
Group level
Eukaryota
Group Name
Endo-alpha mannosidase
Functional Category
  • E: Amino acid transport and metabolism
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 2 entries
Gene Ontology
alpha-mannosidase activity
hydrolase activity, acting on glycosyl bonds
Displaying 1 entry
InterPro
Glycosyl hydrolase family 99
KEGG BRITE Database
Orthology
K15538
Name
glycoprotein endo-alpha-1,2-mannosidase [EC:3.2.1.130]
References
Rhea

RHEA:54824

H2O
α-D-glucosyl-(1→3)-D-mannopyranose
Enzyme
PMID
Disease
Disease Ontology
Displaying all 3 entries
DO ID Disease Name Source
DOID:2030 anxiety disorder
DOID:594 panic disorder
DOID:9975 cocaine dependence
Ortholog
Displaying entries 21 - 30 of 86 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
100538669 MELGA06171
100561214 ANOCA01300
100598520 NOMLE26953
100666598 LOXAF20741
100682532 CRIGR03795
100709960 ORENI31086
100718937 CAVPO16936
100925449 SARHA19335
100946975 OTOGA04403
100996027 PANPA34903
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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025