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MIRAGE
tissue factor pathway inhibitor 2
Summary
- Gene Symbol
-
- TFPI2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Blood coagulation
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Reference proteome
- Repeat
- Secreted
- Serine protease inhibitor
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P48307 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| blood coagulation | ||
| negative regulation of peptidase activity |
|
|
| cellular response to fluid shear stress |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular space | ||
| extracellular matrix |
| GO Term | Evidence Code | PMID |
|---|---|---|
| serine-type endopeptidase inhibitor activity | ||
| extracellular matrix structural constituent |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- kunitz-type serine protease inhibitor
- Functional Category
-
- M: Cell wall/membrane/envelope biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| peptidase inhibitor activity |
| serine-type endopeptidase inhibitor activity |
| InterPro |
|---|
| Pancreatic trypsin inhibitor Kunitz domain superfamily |
| Pancreatic trypsin inhibitor Kunitz domain |
| Proteinase inhibitor I2, Kunitz, conserved site |
Disease
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 7035 | FB:FBgn0033355 | ||
| 7980 | Xenbase:XB-GENE-1002090 | ||
| 21788 | FB:FBgn0033355 | ||
| 21789 | Xenbase:XB-GENE-1002090 | MOUSE51017 | |
| 29436 | FB:FBgn0033355 | ||
| 78239 | WB:WBGene00008304 | ||
| 178891 | FB:FBgn0051515 | ||
| 180656 | FB:FBgn0051515 | ||
| 260212 | FB:FBgn0051515 | ||
| 286926 | RATNO29651 |
