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cholesterol 25-hydroxylase like 1, tandem duplicate 2

Summary

Gene Symbol

ch25hl1.2

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

798384

PubChem

798384

Alliance of Genome Resources

ZFIN:ZDB-GENE-050419-90

Annotation

Keyword

Endoplasmic reticulum
Glycoprotein
Iron
Metal-binding
Monooxygenase
Reference proteome
Sterol biosynthesis
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A0A223M0M0
Q1LX59

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 7** of 7 in total

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GO Term	Evidence Code	PMID
sterol biosynthetic process	IBA
sterol biosynthetic process	IEA

GO Hierarchy

biological process

metabolic process [inference]

biosynthetic process [inference]

organic substance biosynthetic process [inference]

lipid biosynthetic process

steroid biosynthetic process

sterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

primary metabolic process [inference]

lipid metabolic process

steroid metabolic process

steroid biosynthetic process

sterol biosynthetic process

sterol metabolic process [inference]

lipid biosynthetic process

steroid biosynthetic process

sterol biosynthetic process

small molecule metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

organic substance metabolic process [inference]

lipid metabolic process

steroid metabolic process

steroid biosynthetic process

sterol biosynthetic process

sterol metabolic process [inference]

lipid biosynthetic process

steroid biosynthetic process

sterol biosynthetic process

organic cyclic compound metabolic process [inference]

steroid metabolic process

steroid biosynthetic process

sterol biosynthetic process

sterol metabolic process [inference]

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

sterol biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process

steroid biosynthetic process

sterol biosynthetic process

organic cyclic compound biosynthetic process [inference]

steroid biosynthetic process

sterol biosynthetic process

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

organic hydroxy compound metabolic process [inference]

alcohol metabolic process [inference]

secondary alcohol metabolic process [inference]

cholesterol metabolic process

sterol metabolic process [inference]

organic hydroxy compound biosynthetic process [inference]

sterol biosynthetic process

Displaying **all 3** entries
GO Term	Evidence Code	PMID
endoplasmic reticulum	IEA
endoplasmic reticulum membrane	IBA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

endoplasmic reticulum membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

endoplasmic reticulum

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
C-4 methylsterol oxidase activity	IBA
monooxygenase activity	IEA
iron ion binding	IEA
steroid hydroxylase activity	IBA
oxidoreductase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

oxidoreductase activity

monooxygenase activity

steroid hydroxylase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen [inference]

C-4 methylsterol oxidase activity

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen [inference]

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen [inference]

C-4 methylsterol oxidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

iron ion binding

Gene Ontology information from NCBI Gene and UniProt.

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Last updated: April 6, 2026

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