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Guidelines

MIRAGE

protein tyrosine phosphatase receptor type Fb

Summary

Gene Symbol

ptprfb

Organism

Danio rerio (zebrafish)

External Links

NCBI Gene

799867

PubChem

799867

Alliance of Genome Resources

ZFIN:ZDB-GENE-060503-530

Annotation

Keyword

Cell adhesion
Disulfide bond
Glycoprotein
Heparin-binding
Immunoglobulin domain
Protein phosphatase
Proteomics identification
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

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UniProt	Protein Name
A0A8M3AX63
A4IFW2
A0A8M3AQ61
A0A8M3AQ53
A0A8M3AQ56
A0A8M3APL8
A0A8M3APM3
A0A8M3B074
A0A8M3B7N0
A0A8M3B069

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
protein dephosphorylation	IEA
cell adhesion	IEA
signal transduction	IBA
nervous system development	IBA
dephosphorylation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

protein dephosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular process [inference]

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

synaptic membrane adhesion

signal transduction

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation

protein dephosphorylation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance [inference]

sensory neuron axon guidance

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA
membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

plasma membrane

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GO Term	Evidence Code	PMID
phosphoprotein phosphatase activity	IEA
protein tyrosine phosphatase activity	IBA
protein tyrosine phosphatase activity	IEA
non-membrane spanning protein tyrosine phosphatase activity	IEA
heparin binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

histone modifying activity [inference]

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

binding [inference]

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

heparin binding

sulfur compound binding [inference]

heparin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Receptor-type tyrosine-protein phosphatase S

Functional Category

G: Carbohydrate transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
dephosphorylation
hydrolase activity
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity

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InterPro
Fibronectin type III superfamily
Fibronectin type III
Immunoglobulin I-set
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Protein-tyrosine phosphatase, active site
Protein-tyrosine phosphatase, catalytic

Ortholog

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Saccharomyces cerevisiae S288C	5778	SGD:S000000877
Drosophila melanogaster	5789	FB:FBgn0000464
Homo sapiens	5792	Xenbase:XB-GENE-495325	HUMAN49325
Drosophila melanogaster	5802	FB:FBgn0000464
Saccharomyces cerevisiae S288C	19264	SGD:S000000877
Saccharomyces cerevisiae S288C	19266	SGD:S000000877
Mus musculus	19268	Xenbase:XB-GENE-495325	MOUSE41361
Saccharomyces cerevisiae S288C	19270	SGD:S000000877
Saccharomyces cerevisiae S288C	19272	SGD:S000000877
Saccharomyces cerevisiae S288C	19273	SGD:S000000877

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.4.0

Last updated: December 8, 2025